esophageal cancer is one of the most common malignancies with a growing occurrence . it presently ranks ninth among the most frequent cancers in the world and the sixth leading cause of death from cancer . for a variety of reasons, the mainstream of patients with esophageal cancer is actually not suitable for esophagectomy. more than 50% have locally advanced unresectable or metastatic tumors a...

Introduction/Background The treatment options for resectable oropharyngeal (OP) carcinomas are diverse and include surgery, with or without postoperative radiation therapy (PORT)/chemoradiotherapy (based on pathologic findings and patient factors), or definitive radiation therapy/chemoradiotherapy with or without adjuvant surgery (based on posttreatment imaging or biopsy findings). There is no ...

Despite significant improvement over recent decades, oesophageal cancer survival rates remain poor. Neoadjuvant chemoradiotherapy followed by oesophageal resection is mainstay of therapy for resectable oesophageal tumours. Operative morbidity and mortality associated with oesophagectomy remain high and complications arise in up to 60% of patients. Management strategies have moved towards defini...

Introduction. In locally advanced cancers of the cervix, endometrium and vulva, radiotherapy is primary treatment modality. recent years, new modern techniques external radiation have been developed in oncology, with goal dose escalation to target volume, while sparing healthy tissues. The aim this study determine impact volumetric modulated arc therapy on clinical outcomes patients gynecologic...

BACKGROUND The purpose of this study was to present our experience utilizing cetuximab and platinum-based concurrent chemoradiotherapy for the definitive treatment of head and neck squamous cell carcinoma (HNSCC). METHODS Patients (n = 177) who received definitive concurrent chemoradiotherapy for HNSCC were stratified into 3 groups: receiving cetuximab monotherapy (n = 24), cetuximab and chem...

BACKGROUND The purpose of this study was to compare patient-reported outcomes between patients treated by initial transoral resection versus definitive chemoradiotherapy for oropharyngeal cancer. METHODS Thirty-one patients with oropharyngeal cancer treated by initial transoral CO2 laser microsurgery (n = 16) or robotic surgery (n = 15) followed by postoperative radiotherapy were identified. ...