BACKGROUND Studies of cancer survival by population-based cancer registries are a key component in monitoring progress against cancer. Patients notified by death certificates only (DCO) are commonly excluded from such studies. The validity of this "exclude DCO" approach has been questioned and an alternative "correct for DCO" approach has been proposed. METHODS We assess the validity of both ...

in this paper, a new high dynamic range digitally-controlled oscillator (dco) for all-dpll systems is proposed. the proposed dco is based on using a δς modulator as a digital-to-analog converter. using δς dac can provide a very high resolution (18-bit) control on the dco. the δς dac output is a 2-level pulse signal that needs to be filtered for cancelling the out of band shaped noise. the used ...

RATIONALE Flight attendants who worked on commercial aircraft before the smoking ban in flights (pre-ban FAs) were exposed to high levels of secondhand smoke (SHS). We previously showed never-smoking pre-ban FAs to have reduced diffusing capacity (Dco) at rest. METHODS To determine whether pre-ban FAs increase their Dco and pulmonary blood flow (Qc) during exercise, we administered a symptom-...

Abstract: In this paper, CMOS digitally controlled oscillator (DCO) design is analyzed for 4-16 bits. The CMOS DCO is designed based on a ring oscillator. Simulations of the analyzed DCO using 250nm CMOS technology achieve controllable different frequency range with a wide linearity. A 4-bit digitally controlled CMOS oscillator (DCO) design is best by adjusting the width of p-MOS and n-MOS devi...

In this paper, a new differential delay cell is proposed and 16-bit Digital Controlled Oscillator (DCO) based on proposed delay cell is designed. The 16-bit DCO consist of 4-stages differential delay cell in ring structure and a digital control scheme has been used to improved noise characteristics. The structure of the DCO utilizes dual delay path techniques to achieve high oscillation frequen...

The aim of this study was to test the hypothesis that carbon monoxide diffusing capacity (DCO) is elevated in asthmatic patients with minimal airflow limitation and/or hyperinflation; the latter factors should reduce the possibility of technical errors in the measurement of DCO. In ten asthmatic and ten healthy subjects, DCO and its components, membrane diffusing capacity (Dm) and pulmonary cap...

UNLABELLED STUDY SETTINGS AND INTERVENTIONS: Sixty individuals complaining of dyspnea on exertion, but with normal spirometry and lung volumes and normal chest roentgenograms were reviewed for this study. These individuals were selected from a large group of outpatients (552 individuals over a seven-year period) who were referred to our laboratory for exercise testing to determine the cause of ...

BACKGROUND Single breath diffusing capacity for carbon monoxide (Dco) is commonly used as a simple method of assessing overall pulmonary gas exchange properties. Studies of Dco in bronchial asthma have yielded conflicting results. OBJECTIVE To study Dco and to determine the factors influencing Dco in patients with asthma. METHODS Dco was prospectively measured in 80 consecutive never-smoker...

To model lung nitric oxide (NO) and carbon monoxide (CO) uptake, a membrane oxygenator circuit was primed with horse blood flowing at 2.5 l/min. Its gas channel was ventilated with 5 parts/million NO, 0.02% CO, and 22% O2 at 5 l/min. NO diffusing capacity (Dno) and CO diffusing capacity (Dco) were calculated from inlet and outlet gas concentrations and flow rates: Dno = 13.45 ml.min(-1).Torr(-1...