The aim of the present study was to construct a mathematical model to predict the changing trends of cardiac hypertrophy at gene level. Microarray data were downloaded from Gene Expression Omnibus database (accession, GSE21600), which included 35 samples harvested from the heart of Wistar rats on postoperative days 1 (D1 group), 6 (D6 group) and 42 (D42 group) following aorta ligation and sham ...

at a commercial feed mill and were of similar nutritional composition. Feed form variations were made my grinding a portion of the pellets produced for each diet phase. The HQP diets averaged 78.6% intact pellets and the GP diets averaged a 1,108 micron particle size. On D42, YP1 improved ending weight (EW; P=0.022) and feed conversion ratio (FCR; P=0.022). However, no YP Carryover effect was d...

A novel adjuvant (Immunoboost®) to enhance antibody titer response to a commercial vaccine (Lysigin®) against Staphylococcus aureus mastitis in dairy heifers was evaluated. In Phase 1, hyper-immunization with Lysigin® to enhance serum titers did not result in titers that exceeded conventional immunization. In Phase 2, anti-S. aureus titers in heifers immunized with Lysigin® + Immunoboost® tende...

Biologics have transformed the management of moderate-to-severe psoriasis; however, none are curative, and an increasing number patients failed all available classes. MSCs, multipotent stem cells with immunomodulatory properties been used to treat immune-mediated inflammatory diseases including rheumatoid arthritis Crohn disease. We investigated efficacy safety umbilical cord-derived MSCs in 2 ...

I reconsider Stiglitz’s (1977) problem of monopolistic insurance with a continuum of types. Using a suitable transformation of control variables I obtain an analytical characterization of the optimal insurance policies. Closed form solutions and comparative statics results for special cases are provided. JEL: D42, D82

The reason for weight loss at high altitudes is largely unknown. To date, studies have been unable to differentiate between weight loss due to hypobaric hypoxia and that related to increased physical exercise. The aim of our study was to examine the effect of hypobaric hypoxia on body weight at high altitude in obese subjects. We investigated 20 male obese subjects (age 55.7 +/- 4.1 years, BMI ...

Theoretically and experimentally, we generalize the analysis of acquiring a company (Samuelson and Bazerman 1985) by allowing for competition of both buyers and sellers. Näıvety of both is related to the idea that higher prices exclude lower qualities. While competition of näıve buyers increases prices, competition of näıve sellers promotes efficiency enhancing trade. Our predictions are tested...