Let R be a prime ring with center Z, I nonzero ideal of and D: × → symmetric bi–(α, α)-derivation d the trace D. In present paper, we have considered following conditions: i) [d(x), x]α,α = 0, ii)[d(x), ⊆ Cα,α, iii)(d(x), x)α,α iv)D1(d2(x), x) v)d1(d2(x)) f(x), for all x, y ∈ I, where D1 D2 are two bi-(α, α)-derivations, d1, d2 traces D1, respectively, B: is bi-additive mapping, f B.

We report a structure-based biological approach to identify the proton-transfer pathway in photosystem II. First, molecular dynamics (MD) simulations were conducted analyze H-bond network that may serve as Grotthuss-like proton conduit. MD show D1-Asp61, acceptor of H2O at Mn4CaO5 cluster (W1), forms an via one water molecule with D1-Glu65 but not D2-Glu312. Then, D1-Glu65, D2-Glu312, and adjac...

background: esophageal squamous cell carcinoma (escc) is one of the lethal cancers with a high incidence rate in asia. many genes including cyclin d1 and p16 play important role in its carcinogenesis. we aimed to analyze the expressions of cyclin d1 and p16 with the various clinicopathological characteristics of escc.   method: we examined 30 biopsy samples of escc for cyclin d1 and p16 protein...

Objective(s): Hepatocellular carcinoma (HCC) is one of the most significant health condition around the world. As the only curative therapies, liver transplantation and surgical resection are the clinical treatments of HCC. Due to the systemic toxicity and severe side effects of these treatments, it is vital to establish new therapeutic approaches. The present study ai...

Background & Objective: Glioblastoma-multiforme is the high grade form of astrocytic tumors with a short survival time, which are the most common type of brain tumors. Therefore, finding new therapeutic options is essential. Cyclin D1 is expressed in some human malignancies and can be a potential target for therapeutic intervention. The aim of the present study was to determine...

  Background and Objective: Esophageal cancer especially squamous cell carcinoma (SCC) is one of the most common gastro intestinal malignancies in north part of Iran (Khorasan). The standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. Then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. Sever...

background and objective: esophageal cancer especially squamous cell carcinoma (scc) is one of the most common gastro intestinal malignancies in north part of iran (khorasan). the standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. several ...