the objective of the current study was to develop and optimize a sublingual tablet formulation of captopril which is an effective drug in the treatment of hypertension. captopril containing tablets were prepared by direct compression method using different ingredients such as polyvinyl pyrrolidone, starch 1500, sodium starch glycolate and lactose (independent variables) and magnesium stearate, ...

The objective of the current study was to develop and optimize a sublingual tablet formulation of captopril which is an effective drug in the treatment of hypertension. Captopril containing tablets were prepared by direct compression method using different ingredients such as polyvinyl pyrrolidone, starch 1500, sodium starch glycolate and lactose (independent variables) and magnesium stearate, ...

The objective of the current study was to develop and optimize a sublingual tablet formulation of captopril which is an effective drug in the treatment of hypertension. Captopril containing tablets were prepared by direct compression method using different ingredients such as polyvinyl pyrrolidone, starch 1500, sodium starch glycolate and lactose (independent variables) and magnesium stearate, ...

Consider a Bayesian optimal design with many support points which poses the problem of collecting data with a few number of observations at each design point. Under such a scenario the asymptotic property of using Fisher information matrix for approximating the covariance matrix of posterior ML estimators might be doubtful. We suggest to use Bhattcharyya matrix in deriving the information matri...

In this paper, a manipulability analysis of a new parallel-type rolling mill, named ‘‘paramill,’’ in its conceptual design stage is investigated. The paramill considered uses two Stewart platforms (SPs) in opposite directions for the generation of 6 degree-offreedom motions of individual work-rolls. The objective of this new approach is to pursue an integrated control of the strip thickness, st...

A general framework for multi-criteria optimal design is presented which is well suited for performancebased design of structural systems operating in an uncertain dynamic environment. A decision theoretic approach is used which is based on aggregation of preference functions for the multiple, possibly con#icting, design criteria. This allows the designer to trade o! these criteria in a control...