The study measured haematological and cytogentic parameters in workers occupationally exposed to cement dust in order to test the hypothesis that cement dust exposure may perturb these functions. Assessments of haematological, and cytogentic were performed in 30 workers occupationally exposed to cement dust and 30 matched unexposed controls. The RBC level has no significant change and WBC level...

the chromosome number and type as well as karyotype in vimba vimba persa were studied. a total of 200 larvae and 10 fingerlings of this species with an average weight of 30.2g obtained from shahid ansari fish hatchery. to arrest mitosis in metaphase, larvae under study were placed in a 0.05% solution of colchicine for a period of 6h while the fingerlings were given an intramuscular injection of...

To The Editor, Since the introduction of imatinib mesylate as treatment for chronic myeloid leukemia (CML) there have been increasing reports of patients developing Philadelphia (Ph) chromosome negative cytogentic clones, a rare phenomenon in the pre-imatinib era. We wish to report our experience of patients who developed Ph negative clones whilst on imatinib therapy, and briefly review the pot...

This study was carried out to investigate the effect of Ethanol extract of the seeds of Annona muricata on some meiotic parameters in the pest grasshopper Zonocerus variegatus. Adult grasshoppers were treated with 28μl of the Ethanol extract of sun dry seeds of Annona muricata and absolute ethanol (control) for 48 hours and all the parameters (chiasma frequency, formation of rod and ring shaped...

BACKGROUND Acute lymphoblastic leukemia (ALL) is a heterogeneous disease which requires a risk-stratified approach for appropriate treatment. Specific chromosomal translocations within leukemic blasts are important prognostic factors that allow identification of relevant subgroups. In this study, we developed a multiplex RT-PCR assay for detection of the 4 most frequent translocations in ALL (B...