background and objectives: primary amenorrhea is not a disease but a symptom that may result from several quite different causes[nn1] . common hormonal cause of primary amenorrhea includes constitutional delay, hypothalamic –pituitary dysfunction, chronic systemic disease and absent ovarian function. the aim of this study was to estimate the incidence of the chromosomal abnormality referred for...

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Chronic Myeloid Leukemia (CML) is a hematopoietic malignancy characterized by the presence ofPhiladelphia (Ph1) chromosome that results from balanced reciprocal translocation between chromosomes9 and 22 leading in the formation of bcr/abl fusion gene. The present study was conducted to evaluate cytogenetic and molecular abnormalities in CML patients at presentation and during the co...

Background & Aim: Alhagi genus has two important  medicinal plant species in Iran, including Alhagi pseudoalhagi, and A. graecorum (known “Kharshotor” in Persian). These plants are distributed in Iran like weeds. Generally, Alhagi is used as an anti-hemorrhoid, laxative and diuretic. Manna in both species produced by activity of a kind of insect on <...

Background: Acute lymphoblastic leukemia (ALL) is the sixth most common malignancy in Iran. Cytogenetic analysis of leukemic blasts plays an important role in classification and prognosis in ALL patients. The purpose of this study was to define the frequency of chromosomal abnormalities of ALL patients in adults and children in Fars province, Iran.Methods: In this cross-sectional study, we eval...

  Background and Objectives: Primary amenorrhea is not a disease but a symptom that may result from several quite different causes[NN1] . Common hormonal cause of primary amenorrhea includes constitutional delay, hypothalamic –pituitary dysfunction, chronic systemic disease and absent ovarian function. The aim of this study was to estimate the incidence of the chromosomal abnormality referred ...

Background & Aim: Alhagi genus has two important  medicinal plant species in Iran, including Alhagi pseudoalhagi, and A. graecorum (known “Kharshotor” in Persian). These plants are distributed in Iran like weeds. Generally, Alhagi is used as an anti-hemorrhoid, laxative and diuretic. Manna in both species produced by activity of a kind of insect on <...

Background & Objective: Cytogenetic abnormalities in Multiple myeloma (MM) has emerged as the most important factor that determine the prognosis and survival. Fluorescence in situ hybridization (FISH) can detect a greater number of cytogenetic abnormalities as compared to conventional karyotyping and hence has become the standard test in determining genetic abnormalities in MM....