Endocervical samples were obtained from 435 females for Chlamydia detection by using both a Dacron swab and a cytobrush. Positive results were obtained from 35 swabs and 34 cytobrush specimens. All specimens positive with the cytobrush were detected also with swab samples. The cytobrush and Dacron swab appear to be comparable for the detection of endocervical infections with Chlamydia trachomatis.

In 899 women attending a genitourinary medicine clinic Chlamydia trachomatis was tested for using both a Cytobrush and a conventional swab. In 425 cases, the Cytobrush was used for concurrent cytology and chlamydia sampling. Both methods were equally effective in the detection of chlamydia, and, in addition, the Cytobrush gave a higher yield of inclusion bodies per sample. The use of the same i...

BACKGROUND In women with cancer-related hysterectomy, the vaginal vault cytology has a low efficacy - when performed by conventional methods - for the early detection of vaginal recurrence. The amount of exfoliated cells collected is generally low because of atrophy, and the vaginal vault corners can be so narrow that the commonly used Ayres spatula cannot often penetrate deeply into them. This...

484 Abstract A total of 49 patients were included in this study, 29 patients with oral benign and malignant lesions, and 20 healthy individuals were included as control. All these cases were examined by using cytobrush technique. The study aimed to evaluate the sensitivity and specificity of cytobrush method in the detection of precancerous and cancerous lesions of oral mucosa. The results of ...

Cyclic adenosine monophosphate (cAMP) is a second messenger that may be associated with olfactory function. No known studies have compared existing collection methods for determining nasal cAMP levels. This is a prospective study comparing the comfort and reliability of the nasal curette and cytobrush. A secondary outcome collected for feasibility testing was characterizing the association betw...

BACKGROUND Cervical cancer is the third most common cancer in women in the world. Papanicolaou smear is known as a standard test for cervical cancer screening; however, the most important challenge is high rates of false negative results. The aim of this study was to compare the quality of smears obtained by anatomical spatula and spatula-cytobrush. The most important factor in false negative r...

Blood samples are an excellent source of large amounts of genomic DNA. However, alternative sources are often needed in epidemiological studies because of difficulties in obtaining blood samples. This report evaluates the buccal cytobrush and alcohol-containing mouthwash protocols for collecting DNA by mail. Several DNA extraction techniques are also evaluated. The study was conducted in two ph...

Papanicolaou smears have false-negative rates of 6 percent to 56 percent that are due, in large part, to inadequate sampling of endocervical cells. A randomized, prospective trial was conducted comparing the adequacy of Papanicolaou smears obtained with the cytobrush and Ayre spatula with smears obtained with the extended-tip spatula, as measured by the presence of endocervical cells. One hundr...

Objective: This prospective study aims to compare three different sampling techniques for the collection of endometrial cytological specimens in the mare: the guarded culture swab, the uterine cytobrush and the low volume uterine flush. Material and methods: The study po pulation consisted of six healthy Standardbred mares in dioestrus. In each mare an acute endometritis was induced by performi...