Background: Infertility problem affects 20-30% of young couples. One of the known causes of spermatogenesis disorder is chemotherapy in patients with cancer which its side effect may last up to the end of the life. The aim of the present study is to investigate the effect of GnRH on viability of ovarian follicles defect produced by anticancer drug. Materials and Methods: In the present study ad...

BACKGROUND Having demonstrated in a previous report that the response of circulating epithelial tumor cells (CETC) during the first cycles of primary (neoadjuvant) chemotherapy perfectly reflects the response of the tumor, in the present study the changes in cell numbers during subsequent cycles and their possible impact on the therapy's outcome were examined. PATIENTS AND METHODS In 58 breas...

Sowohl die hämatopoetische Stammzelltransplantation (HSCT) als auch eine Therapie mit Cyclophosphamid sind Behandlungsoptionen für progressive interstitielle Lungenerkrankungen (ILD) im Zusammenhang systemischer Sklerose (SSc). Ciaffi et al. bewerteten Entwicklung der SSc-ILD bei Patienten, HSCT erhielten und verglichen den Erfolg jenem von einnahmen.

Mục tiêu: Mô tả đặc điểm lâm sàng, cận sàng của bệnh nhân ung thư vú được điều trị bằng Cyclophosphamid. Đối tượng và phương pháp: nghiên cứu thuần tập tiến mô tả, theo dõi dọc trên 68 tại Bệnh viện Thành phố Thủ Đức phác đồ có Cyclophosphamid từ 4 -6 chu kỳ. Kết quả: Tự khám thấy khối u là triệu chứng cơ năng phổ biến nhất với 67,65%. Vị trí thường gặp ở nhóm 1/4 ngoài (54,41%). Tỷ lệ hạch nác...

BACKGROUND Astragalus polysaccharides (APS) are active constituents of Astragalus membranaceus. They have been widely studied, especially with respect to their immunopotentiating properties, their ability to counteract the side effects of chemotherapeutic drugs, and their anticancer properties. However, the mechanism by which APS inhibit cancer and the issue of whether that mechanism involves t...

Background: Cyclophosphamid as an anti-neoplastic medicine, is classified as a derivative of mustard nitrogen, which passes through brain- blood -barrier and it is known as causing significant poisoning affects with high stoppage effects on body. Through attaching two DNA chains of cell nucleus and breaking inter/intra-chain connection and inhibition RNA synthesis Cyclophosphamide causes high t...