objective: cell vital function has correlation with mechanical loadings that cell experiences. here, effects of in-vitro combined cyclic-static stretch on proliferation of human mesenchymal stem cell (hmsc) were evaluated. materials and methods: hmscs were cultured on gelatin coated elastic membranes, and exposed to stretch loading. four different regimes of cyclic, static, combined cyclic-sta...

in this research, softening and ratcheting behaviors of ck20 alloy steel cylindrical shells were studied under displacement-control and force-control cyclic axial loading and the behavior of hysteresis curves of specimens was also investigated. experimental tests were performed by a servo-hydraulic instron 8802 machine. the mechanical properties of specimens were determined according to astm e8...

In this paper, ratcheting behavior of beams subjected to mechanical cyclic loads at elevated temperature, using the rate dependent Chaboche unified viscoplastic model with combined kinematic and isotropic hardening theory of plasticity, is investigated. A precise and general numerical scheme, using the incremental method of solution, is developed to obtain the cyclic inelastic creep and plastic...

The spine is routinely subjected to repetitive complex loading consisting of axial compression, torsion, flexion and extension. Mechanical loading is one of the important causes of spinal diseases, including disc herniation and disc degeneration. It is known that static and dynamic compression can lead to progressive disc degeneration, but little is known about the mechanobiology of the disc su...

objective: endothelium is a selective and permeable membrane for transferring nutrients and vital components to arterial wall. endothelial damage might lead to altered biological function of endothelium and clinical consequences such as atherosclerosis. blood pressure pulse always exerts circumferential tension to the arterial wall. hence, such tension together with other loads, play important ...

This paper is concerned with analysis for the strengthening effect of carbon fiber-reinforced polymer (CFRP) on steel columns under cyclic lateral loading in thermal environment. Based on the finite element theory of thermo-elastic problem and steel structure stability theory, the hysteretic behavior of axial compression steel columns was studied by using Ansys software. The main variables inve...

Combined in-phase tension/torsion loading was applied to 8-ply 45° 4 E-glass/epoxy composite shafts under monotonic and fatigue conditions to determine the effects of multi-axial loading on its failure. A damage criterion for multi-axial monotonic loading was proposed considering the contribution of both normal and shear stresses on the plane of failure. The experimental data showed an excellen...

During earthquake excitations, reinforced concrete bridge columns can be subjected to a combination of axial load, shear force, flexural moments, and torsional moments. The torsional moment can be much more significant in columns of bridges that are skewed, curved, have unequal spans, or unequal column heights. Combined loading including torsion can result in complex flexural and shear failure ...