The modulatory effects of the Cyclamen trochopterantum tuber extract on hepatic drug-metabolizing enzymes, including aniline 4-hydroxylase (A4H; CYP2E1), ethoxyresorufin O-deethylase (EROD; CYP1A), methoxyresorufin O-demethylase (MROD; CYP1A), caffeine N-demethylase (C3ND; CYP1A2) aminopyrene N-demethylase (APND; CYP2C6), and erythromycin N-demethylase (ERND; CYP3A1), were examined in vivo in r...

Cyclamen persicum (cyclamen) is a commercially valuable, winter-blooming perennial plant. We cloned two cyclamen orthologues of AGAMOUS (AG), CpAG1 and CpAG2, which are mainly expressed in the stamen and carpel, respectively. Cyclamen flowers have 5 petals, but expression of a chimeric repressor of CpAG1 (CpAG1-SRDX) caused stamens to convert into petals, resulting in a flower with 10 petals. B...

Cyclamen coum is a traditional medicinal plant in the Turkey. Its anticancer properties and whether cyclamen extract induces any cytotoxicity in solid cancer cell lines have not been thoroughly investigated previously. Therefore we examined cytotoxic effects on cervical cancer, HeLa, and non small cell lung cancer cell, H1299, lines. Cyclamen extract induced cellular death of both HeLa and H129...

Although interspecific hybrids between cyclamen (Cyclamen persicum) cultivars and C. purpurascens were produced by using the ovule culture, mode of inheritance of flower pigment remains obscure. Therefore, inheritance of anthocyanin in the petals in the crosses between diploid cyclamen cultivars and C. purpurascens was investigated in the present study. In every cross combination, including the...

The biological effects of heavy-ion beam irradiation on cultured tissues of cyclamen were investigated by establishing an irradiation-mediated mutation breeding protocol for producing a new variety of cyclamen. Initially, a callus, a somatic embryo, and a plantlet were irradiated with C ion beam at doses of 10, 20, 40, 60, and 80 Gy. Distinct mutants were not obtained in plants regenerated from...

An efficient protocol for callus induction and somatic embryogenesis of Cyclamen premium Mill. Was developed. In this study we investigate difference between response of two explants type leaf and petiole and two medium salt concentrations MS and 1⁄2 MS on callus percentage and somatic embryo number. Media was non-significant on callus production but leaf explants was better than petiole and in...

Submit Manuscript | http://medcraveonline.com main component of flower color is anthocyanin, a type of flavonoid [1]. Numerous genes involved in anthocyanin biosynthesis have been analyzed in various plants, and their biosynthesis pathways determined [2,3]. In addition to anthocyanins, flavonols and organic acids also play a role in flower color as ‘co-pigments’ [4]. Fragrant cyclamen cultivars...

Reduced levels of trienoic fatty acids (TAs) in chloroplast membranes induce thermotolerance in several plant species, but the underlying mechanisms remain unclear. TA peroxidation in plant cell membranes generates cytotoxic, TA-derived compounds containing α,β-unsaturated carbonyl groups. The relationship between low TA levels and the amounts of cytotoxic TA-derived compounds was examined usin...

Several pre-germination treatments were given to Cyclamen persicum Mill. seed with the objective of improving germination percentage, speed, and uniformity. Soaking seed in water and in gibberellic acid improved germination speed, but the latter reduced survival. Etridiozole, benomyl, thiram, and sodium hypochlorite treatments did not reduce or delay germination as has been reported elsewhere, ...

Submit Manuscript | http://medcraveonline.com main component of flower color is anthocyanin, a type of flavonoid [1]. Numerous genes involved in anthocyanin biosynthesis have been analyzed in various plants, and their biosynthesis pathways determined [2,3]. In addition to anthocyanins, flavonols and organic acids also play a role in flower color as ‘co-pigments’ [4]. Fragrant cyclamen cultivars...