introduction: this study was done to compare the efficacy of interlesional injection of glucantime method and cryotherapy with interlesional injection in treatment of cutaneous leishmaniasis in qom province. methods: in this randomized controlled trial patients were randomly allocated in the two arms of the study:one receiving interalesional glucantime injection weekly and the other receiving b...

BACKGROUND Cutaneous leishmaniasis can be caused by several Leishmania species and is transmitted to human beings and animals by sand flies, Down syndrome is known to cause immunodeficiency that might lead to increase the susceptibility to infection with Leishmania.Up to our knowledge this is the first case of isolated facial cutaneous leshmaniasis in association with Down syndrome. CASE PRES...

Studies on new drugs for malaria, trypanosomiasis, filariasis, tuberculosis, schistosomiasis, leshmaniasis and amoebiasis came almost to a standstill; while there is no suitable drug to stop the emerging, re-emerging and the drug-resistant pathogens. On the other hand, the clinical efficacy of many ethnomedicines or compounds of natural origin was not yet evaluated and the composition of many t...

Brazilian mucosal leshmaniasis is briefly reviewed, emphasis being given to recent advances clinical management. Patients continue to occupy much hospital bed space and in some cases are notoriously difficult to treat. Indefinite follow up is recommended. Many aspects of the aetiology remain mysterious although Leishmania (Viannia) braziliensis is the most common organism isolated. Perspectives...

Aim: To see the efficacy of meglumine antimoniate alone in comparison with combination and CO2 ablative laser among patients cutaneous leishmaniasis. Study design: Quasi-experimental study. Place duration study: Department Dermatology, Pakistan Emirates Military Hospital, Rawalpindi from 9th July 2020 to 8th January 2021. Methodology: Sixty (30 each group) diagnosed cases leishmaniasis by skin ...

Nanoemulsions are drug delivery systems that may increase the penetration of lipophilic compounds through the skin, enhancing their topical effect. Chalcones are compounds of low water solubility that have been described as promising molecules for the treatment of cutaneous leishmaniasis (CL). In this context, the aim of this work was to optimize the development of a nanoemulsion containing a s...

systemic sclerosis is a generalized disorder of connective tissue, in which the pattern of disease extent, progression and outcome is heterogenous. to determine clinical features, disease extent and progression, we studied our patients in two phases of disease early (the first 3 years) and late phases (after 6 years of disease). 19 patients had diffuse cutaneous and 34 patients had limited cuta...