with Hypaque was performed before the expected date of ovulation, and laparoscopy before menstruation.' All but one of the laparoscopies were performed under local anaesthesia2 with about 30 ml aqueous methylene blue injected under low pressure into the uterine cavity. On laparoscopy the dye could be seen traversing patent tubes and spilling into the pouch of Douglas. Bilateral tubal patency wa...

Iatrogenic Cushing's syndrome is an undesirable outcome of glucocorticoids treatment. It can be increased by pharmacologic interactions. Glucocorticoid therapy, given in association with ritonavir, and some azole treatments are causes of iatrogenic Cushing's syndrome. We present a patient with common-variable immunodeficiency who received 7 years of itraconazole therapy for bronchial colonizati...

A girl who developed Cushingoid features in peripuberty, but was eucortisolemic, was previously reported to have markedly elevated lymphocyte glucocorticoid receptor sites per cell with normal binding affinity as a potential cause of her phenotype. Her circadian rhythm of cortisol and pituitary-adrenal axis were initially intact, but later proved to be dysregulated. The patient presented at age...

A four month old male infant born with a birth weight of 2.5 kg presented with chickenpox. On examination, he weighed 11 kg and had cushingoid features. His blood pressure was normal and had multiple papulovesicular lesions characteristic of chickenpox. The child had to be treated with oral acyclovir in view of cushingoid features. At fifteen days of life, a private practitioner had prescribed ...