background & importance: the aim of this study was to demonstrate the result of transsphenoid microsurgery for cushing disease in our center and comparing the results in details with other articles, to achieve the best decision for patients management in future. case presentation: between 1991 to 2015, 50 patients suffering from cushing disease were operated. before operation, endocrine tests a...

background: cushing's disease is the most prevalent cause of endogenous adrenocorticotrophic hormone hypersecretion. the aim of this study was to document the current clinical practice pattern in the management of cushing's disease by iranian endocrinologists to determine their opinions and compare them with the current clinical practice guidelines.    methods: an eight-item questionnaire deali...

realizing the cause of cushing's syndrome (cs) is one of the most challenging processes in clinical endocrinology. the long high dose dexamethasone suppression test (standard test) is costly and need an extended inpatient stay. in this study we want to show the clinical utility of the overnight 8 mg dexamethasone suppression test (dst) for differential diagnosis of cs in a referral center. retr...

high cortisol level in endogenous cushing’s syndrome suppresses the immune system and after treatment there may be an over activity of immune reaction leading to autoimmune diseases mostly thyroid and rheumatologic disorders. this is the second reported case of multiple sclerosis developing after treatment of cushing’s syndrome. a 42-year old man is reported who presented with bone fracture and...

harvey cushing: a life in surgery (review) project muse harvey cushing: a life in surgery (review) project muse harvey cushing a life in surgery auzww harvey cushing a life in surgery fesse harvey cushing a life in surgery arctur harvey cushing a life in surgery dietec harvey cushing a life in surgery michael bliss nulet harvey cushing a life in surgery dockscafe harvey cushing a life in surger...

background: cushing's disease is the most prevalent cause of endogenous adrenocorticotrophic hormone hypersecretion. the aim of this study was to document the current clinical practice pattern in the management of cushing's disease by iranian endocrinologists to determine their opinions and compare them with the current clinical practice guidelines.    methods: an eight-item questionn...

Background & Importance: The aim of this study was to demonstrate the result of transsphenoid microsurgery for Cushing disease in our center and comparing the results in details with other articles, to achieve the best decision for patients management in future. Case Presentation: Between 1991 to 2015, 50 patients suffering from Cushing disease were operated. Before operation, endocrine t...

It is sometimes difficult to confirm the location of a microadenoma in Cushing disease. Recently, we experienced an 11-yr-old female case of Cushing disease with hyperprolactinemia. She was referred to our hospital because of decrease of height velocity with body weight gain. On admission, she had typical symptoms of Cushing syndrome. Although no pituitary microadenomas were detected on 1.5 Tes...

BACKGROUND Cushing syndrome is characterized by glucose intolerance, cardiovascular disease, and an enhanced systemic inflammatory response caused by chronic exposure to excess cortisol. Eosinopenia is frequently observed in patients with adrenal Cushing syndrome, but the relationship between the eosinophil count in peripheral blood and indicators of glucose level in patients with adrenal Cushi...