نتایج جستجو برای: cslab

تعداد نتایج: 5  

2015
Tianlei Liu Shoubin Xue Liang Wang

BACKGROUND In Streptococcus mutans, ComCDE, a peptide-induced two-component signal transduction system, forms a closed signal transduction, and even if difunctional ComE closes this signal at its headstream to avoid its infinite amplification, it is not enough for ComE to work in a concentration-dependent manner. CslAB has a chance to regulate ComCDE by controlling extracellular competence-stim...

Journal: :jundishapur journal of microbiology 0
tianlei liu department of biotechnology, school of food and bioengineering, jiangsu university, zhenjiang, china; department of biotechnology, school of food and bioengineering, jiangsu university, zhenjiang, china. tel: +86-51188797059, fax: +86-51188780201 shoubin xue the first people’s hospital of lanzhou city, lanzhou, china liang wang department of biotechnology, school of food and bioengineering, jiangsu university, zhenjiang, china

results pcslab is a weak promoter responding to come and its binding appears to be negative cooperative. although pcslab is partially controlled by comcde, it can respond to comcde regulation. supported by the obtained molecular evidence, cslab acts as a stabilizer of comcde signal on the patterns of its expression. conclusions pcslab is partially controlled by comcde. cslab is a stabilizer of ...

Journal: :Journal of bacteriology 2011
David C I Hung Jennifer S Downey Eduardo A Ayala Jens Kreth Richard Mair Dilani B Senadheera Fengxia Qi Dennis G Cvitkovitch Wenyuan Shi Steven D Goodman

In Streptococcus mutans, both competence and bacteriocin production are controlled by ComC and the ComED two-component signal transduction system. Recent studies of S. mutans suggested that purified ComE binds to two 11-bp direct repeats in the nlmC-comC promoter region, where ComE activates nlmC and represses comC. In this work, quantitative binding studies and DNase I footprinting analysis we...

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