نتایج جستجو برای: crs w np

تعداد نتایج: 241796  

Abstract Introduction: The present study was conducted to investigate the association between the serum vitamin D levels and severity of disease in chronic rhino sinusitis (CRS) patients. Materials and Methods: This prospective cross-sectional study was conducted on a total of 93 patients suffering from chronic rhino sinusitis with nasal polyposis (CRS w NP). Serum level...

Journal: :iranian journal of otorhinolaryngology 0
bijan khademi department of otorhinolaryngology, institute for cancer research, shiraz university of medical sciences, shiraz,iran seyed hossein dastgheib department of otorhinolaryngology, institute for cancer research, shiraz university of medical sciences, shiraz, iran eskandar kamali-sarvestani department of immunology, shiraz university of medical sciences, shiraz, iran

introduction:  il-8 is one of the pro-inflammatory cytokines which can play an essential role in the pathogenesis of chronic rhinosinusitis (crs) as well as nasal polyposis (np). the ability of individuals in producing il-8 is partially determined by il-8-251 a/t polymorphism. hence, the aim of the present study was to investigate the association between il-8-251 a/t and cxcr2 +1208 c/t genes p...

Bijan Khademi, Eskandar Kamali-Sarvestani Seyed Hossein Dastgheib

Introduction:  IL-8 is one of the pro-inflammatory cytokines which can play an essential role in the pathogenesis of chronic rhinosinusitis (CRS) as well as nasal polyposis (NP). The ability of individuals in producing IL-8 is partially determined by IL-8-251 A/T polymorphism. Hence, the aim of the present study was to investigate the association between IL-8-251 A/T and CXCR2 +1208 C/T genes ...

Journal: :Archives of otolaryngology--head & neck surgery 2007
Guo Qiang Ding Chun Quan Zheng Shelly S Bagga

OBJECTIVES To investigate the expression of epidermal growth factor receptor (EGFR) messenger RNA (mRNA) in human sinus mucosa and to compare the expression of EGFR and EGF among patients with chronic rhinosinusitis (CRS), patients with CRS and nasal polyposis (CRS/NP), and a healthy control group. DESIGN Maxillary sinus ostia mucosa was harvested from patients undergoing endoscopic sinus sur...

2017
Sung-Woo Cho Dae Woo Kim Jeong-Whun Kim Chul Hee Lee Chae-Seo Rhee

Chronic rhinosinusitis (CRS) can be classified according to the presence of a nasal polyp (NP): CRS with NP (CRSwNP) and CRS without NP (CRSsNP). CRSwNP has characteristics with high infiltration of tissue eosinophilia with a burst of Th2 inflammatory cytokine. However recent findings in Eastern Asia countries suggest that CRSwNP can be divided according to the presence of tissue eosinophilia. ...

Journal: :Rhinology 2011
P Sahlstrand-Johnson B Ohlsson C Von Buchwald M Jannert Marianne Ahlner-Elmqvist

AIMS This study summarises the health-related quality of life (HRQOL) scores and absenteeism caused by sinus problems in patients awaiting surgery with the diagnoses recurrent acute rhinosinusitis (RARS), chronic rhinosinusitis with nasal polyps (CRS+NP) or CRS without nasal polyps (CRS-NP), in a prospective multi-centre study. METHODOLOGY Two hundred and seven patients with RARS, CRS+NP or C...

Journal: :Journal of investigational allergology & clinical immunology 2010
M E Zernotti N Angel Villegas M Roques Revol C E Baena-Cagnani J E Arce Miranda M E Paredes I Albesa M G Paraje

INTRODUCTION The pathogeny of chronic rhinosinusitis with nasal polyposis (CRS/NP) has not been elucidated. Bacterial exotoxins have been implicated in many inflammatory chronic diseases, such as chronic otitis, chronic tonsillitis, cholesteatomas, and more recently CRS/NP. We propose that the bacteria in CRS/NP are not only present in a planktonic state, but also occur in microbial communities...

2017
Aaron N. Pearlman Rakesh K. Chandra David B. Conley Robert C. Kern

Mounting evidence suggests that nasal polyposis (NP) is a clinical manifestation of multiple possibly coexisting immunologic pathways, and because this entity likely reflects an array of disease states, the epidemiology is difficult to characterize. Phenotypically, chronic rhinosinusitis (CRS) can be classified as either CRS without NP or CRS with NP. CRS without NP, in general, reflects TH1-me...

Journal: :Respiratory Research 2006
Claudina Angela Pérez-Novo Cindy Claeys Paul Van Cauwenberge Claus Bachert

BACKGROUND Eicosanoid receptors are G-protein-coupled receptors playing an important immunomodulatory role in airway diseases. However, there is little information on the expression of these receptors and their link with eosinophilic inflammation in paranasal sinus diseases. We aimed with this study to investigate the tissue expression of leukotrienes and prostaglandin E2 receptors in chronic r...

Journal: :Archives of otolaryngology--head & neck surgery 2008
Jong Hwan Wang Hyun Ja Kwon Yoo-Sam Chung Bong-Jae Lee Yong Ju Jang

OBJECTIVE To investigate the difference in susceptibility to rhinovirus (RV) infection and RV-induced inflammatory response between the nasal mucosae from patients with chronic rhinosinusitis with nasal polyps (CRS/NP) and subjects without CRS/NP (hereinafter, normal subjects). DESIGN In vitro study. SETTING Tertiary care rhinology clinic. PATIENTS We conducted RV infection experiments on...

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