the purpose of this study was to investigate the effect of short term creatine monohydrate supplementation on baseline homocysteine concentrations and following an exhaustive exercise in active men. twelve male students who were members of soccer team of mazandaran university (age: 21.83±2.20 years, bmi: 13.53±58 kg/m2, homocysteine: 13.53±58 ?mol/lit) volunteered to participate in this study. ...

the purpose of this study was to investigate the effects of short-term creatine monohydrate (cr) and folic acid (fa) supplementation on homocysteine (hcy) levels in young active males. eighteen young male soccer players (21.11±2.02 years, vo2max 56.51±2.31, hcy 13.45±0.59) volunteered to participate in this study. they were randomly divided into creatine monohydrate (n=6), folic acid (n=6) and ...

Background Athletes use ergogenic aids in an attempt to increase training-adaptations, which serves to enhance their performance during competition. Creatine monohydrate is one of the most studied ergogenic aids. Although many studies have reported the efficacy and effectiveness of creatine monohydrate supplement manufacturers continually introduce newer forms of creatine into the marketplace. ...

Our objective was to determine the effect of creatine monohydrate on disease progression in patients with amyotrophic lateral sclerosis (ALS). One hundred and seven patients with the diagnosis of probable or definite ALS, of less than five years duration from symptom onset, were randomized to either treatment with daily creatine monohydrate (5 g/d) or placebo. In this multicenter, double-blinde...

BACKGROUND Muscle cramp is a common complication of haemodialysis. The exact mechanism of this complication is still unknown. Many approaches have been used to relieve the muscle cramping but have had variable effects. One of the possible mechanisms of haemodialysis-associated muscle cramps (HAMC) is the disturbance of muscle energy metabolism. Creatine monohydrate can enhance muscle metabolism...

conclusions combination of creatine monohydrate and exercise attenuated inflammation and endothelial dysfunction markers among heart failure patients. patients and methods one hundred patients were prospectively randomized into two groups: intervention group which received 5 grams/day creatine monohydrate and exercised for 8 weeks; and control group which did not receive any interventions. inte...

Alpha-lipoic acid has been found to enhance glucose uptake into skeletal muscle in animal models. Studies have also found that the co-ingestion of carbohydrate along with creatine increases muscle creatine uptake by a process related to insulin-stimulated glucose disposal. The purpose of this study was to determine the effect of alpha-lipoic acid on human skeletal muscle creatine uptake by dire...

We report a case of a heretofore healthy 18-year-old man who presented with a 2-day history of nausea, vomiting and stomach ache while taking creatine monohydrate for bodybuilding purposes. The patient had acute renal failure, and a renal biopsy was performed to determine the cause of increased creatinine and proteinuria. The biopsy showed acute tubular necrosis. In the literature, creatine mon...

the purpose of this study was to investigate the effects of short term creatine monohydrate as an ergogenic supplement on the sprint performance and muscular strength of wrestlers. 20 wrestlers were selected randomly and divided into two groups. one group was placebo group (control) and the other group was creatine supplement group (experimental). in a double blind project, subjects' speed...