fryns-aftimos syndrome is a rare autosomal dominant disorder characterized by craniofacial signs, anterior neuronal migration disorder (pachygyria, lissencephaly), skeletal deformities and mental retardation. we describe a five-year-old boy with abnormal facial features (hypertelorism, ptosis, high arched palate), skeletal problems (short stature, short fingers, flat feet) and mild intellectual...

the robert/sc (pseudothalidomide) syndrome is a rare autosomal recessive disorder, associated with phocomelia and craniofacial abnormalities. an anomalous fetus with lower limb phocomelia and micromelia, lumbar myeloschisis, upper limb and ribs defects and craniofacial abnormalities is reported whose diabetic mother took mebendazole and glibenclamide in early pregnancy. ultrasonographic finding...

some syndromes that are characterized by abnormalities of the skull, facial bones, and mandibule, most of these patients are from the pediatric population. for the anaesthetic management of patients with various craniofacial dysostosis are as follows: 1) the necessary for careful evaluation of the airway by simply observing the patient. 2) evaluation of the patient for abnormalities of the hear...

Subgroups within a population are often difficult to discover and describe except by subjective methods. In this study, cluster analysis (numerical taxonomy) methods were used on selected craniofacial measurements obtained from 308 North American White children of both sexes in the age range 6-18 to derive categories of skeletal facial types. Two different cluster analysis approaches were used ...

Objective: Silybum marianum has been used for centuries in herbal medicine for treatment of liver diseases. Currently, there is no data available on the possible effects of silymarin on fetal development. This study aimed to investigate the teratogenic effect of silymarin on BALB/c mice fetuses. Materials and Methods: A total of 40 pregnant mice were divided into 4 groups of 10 mice each. Three...

Symmetr y and propor t ion plays an impor tan t role in cosmeti c par t of face and golden ra tio depicts a st rong cor rela tion between mathematical propor t ion of face and appearance. Th is can be a ffected by mult iple fa ctor s including syndromes which con tr ibute a sign ifican t role in cran iofacial abnormali ties. Th is paper in tends to br ing out the craniofacial man ifesta t ions ...

objective: silybum marianum has been used for centuries in herbal medicine for treatment of liver diseases. currently, there is no data available on the possible effects of silymarin on fetal development. this study aimed to investigate the teratogenic effect of silymarin on balb/c mice fetuses. materials and methods: a total of 40 pregnant mice were divided into 4 groups of 10 mice each. three...