The genus Cosmos is native of America and is constituted by 34 species; 28 of them are endemic of Mexico. The cosmos are used as a nematicide, antimalarial, and antioxidative agent. The aim of this study was to estimate the genetic diversity among 7 cosmos species based on random amplified polymorphic DNA (RAPD) and inter-simple sequences repeats (ISSR) markers. With RAPD markers, the obtained ...

An important challenge in cancer genomics is precise detection of structural variations (SVs) by high-throughput short-read sequencing, which is hampered by the high false discovery rates of existing analysis tools. Here, we propose an accurate SV detection method named COSMOS, which compares the statistics of the mapped read pairs in tumor samples with isogenic normal control samples in a dist...

We summarise the existing CoSMoS approach to modelling and simulating complex systems, then introduce how the various CoSMoS models are related via their metamodel, and demonstrate the generality of the process by discussing its application to engineering bio-

How should the metaphysical hypothesis of materialism be formulated? What strategies look promising for defending this hypothesis? How good are the prospects for its successful defense, especially in light of the infamous ‘‘hard problem’’ of phenomenal consciousness? I will say something about each of these questions. 1. FORMULATING MATERIALISM In seeking a satisfactory formulation of materiali...

In 2011, a leaf blight disease was observed on cosmos (Cosmos bipinnatus) leaves in Nonsan, Korea. The causal pathogen was isolated and identified based on morphological and molecular approaches. Morphological characteristics of the pathogen matched well with the Alternaria cosmosa and also easily distinguishable from Alternaria zinniae reported from cosmos seeds by producing branched beak. Phy...

Integrating dedicated applications with a wireless LAN and WAN infrastructure, the COSMOS system provides "Construction Site Mobile Operations Support". In this paper, we focus on the approach taken in COSMOS for bandwidth management across the bottleneck satellite WAN link, particularly for supporting video conferencing between company headquarters and construction sites. We discuss the IETF Q...

An integrated modeling and simulation tool called Componentbased System Modeler and Simulator (CoSMoS) is developed. It supports visual development of families of models that have well-defined logical specifications. The logical componentbased models persist in relational databases and may be automatically translated into specific target simulation and markup programming languages. The underlyi...

The ‘Cosmos’ model and its application is a dynamic event distribution system, which generates and organizes sonic entities evolving on multiple time scales. Inspired by the stochastic event generation models that were developed by Iannis Xenakis, the Cosmos model proposes additional important aspects such as the self-similarity in the structure and emergent behaviour in the resulting sonic evo...

CoSMoS is a defined approach for designing, building, and arguing fit for purpose, a scientifically rigorous simulation of a complex real world system. The ODD (Overview, Design concepts, Details) protocol is a standardised way of describing simulation models, defined to support reproducibility. This paper demonstrates that use of the CoSMoS approach to build a simulation supports the presentat...