the effect of cortisone on the experimental gastric ulceration produced by intraperitoneal injection of aspirin in the rat is studied. cortisone has significantly prevented the appearance of aspirin_ induced gastric ulceration. the possible mechanism of this effect of cortisone is discussed.

the effect of cortisone on the experimental gastric ulceration produced by intraperitoneal injection of aspirin in the rat is studied. cortisone has significantly prevented the appearance of aspirin_ induced gastric ulceration. the possible mechanism of this effect of cortisone is discussed.

background:  geographic and doctor-to-doctor variations in care are a focus of quality and safety efforts in medicine. this study addresses factors associated with variation in the rate of operative treatment of de quervain tendinopathy.   methods: we used a database including all patient encounters at 2 large medical centers, to study the experience of 10 hand surgeons and 1 physiatrist workin...

Serial studies of the serum levels of trypsin inhibitor have been performed on monkeys following injection of turpentine-falba, total body irradiation, thermal injury, splenectomy, administration of cortisone acetate and egg albumin. Following the injection of turpentine-falba mixture there was a prompt elevation in the trypsin inhibitor power of the serum. A similar response accompanied the ad...

1. Cortisone, in a dose of 25 mg. daily and with a pretreatment period of 3 days, in rabbits weighing 1 to 1.5 kilos, did not inhibit the dermal Shwartzman reaction produced by meningococcal or S. marcescens toxin. 2. In cortisone-treated rabbits, a single intradermal injection of toxin produced a primary reaction of hemorrhage and necrosis in the skin at the injected site. This lesion resemble...

Injection of ACTH or cortisone has no effect on the amount of fibrinolysin resulting from the activation of profibrinolysin by peptone. Antifibrinolytic activity of serum is significantly increased by ACTH or cortisone but not by desoxycorticosterone or corticosterone. No increase in anti-fibrinolytic power of serum is produced, however, by the injection of ACTH or cortisone in splenectomized g...

In an earlier communication (1), it was shown that treatment with cortisone caused a marked alteration in the response of rabbits to an injection of endotoxin from certain Gram-negative microorganishas. In normal animals, an intradermal injection of meningococcal or Serratia marcescens toxin resulted in a vigorous local inflammatory reaction, with visible erythema and edema of the involved skin...

AIM To report on clinical outcome and complications of intravitreal injection of crystalline cortisone in patients undergoing pars plana vitrectomy for treatment of proliferative vitreoretinopathy. METHODS The study included all 16 patients who underwent pars plana vitrectomy for treatment of proliferative vitreoretinopathy, who received an intravitreal injection of 10-20 mg crystalline triam...

tions of hydrocortisone and cortisone to man have established the plasma half-life of hydrocortisone to be 2 hours and that of cortisone 1 hour (1, 2). From isotopic determinations in urine, the half-life of hydrocortisone in the body has been found to be 6 hours and that of cortisone 3.6 hours (3, 4). Thus, cortisone is not only cleared from the plasma more rapidly than hydrocortisone but it i...

Cortisone is an injected anti-inflammatory drug that can cause painful side effects known as "steroid flares" which are caused by cortisone crystallizing at the injection site. We used molecular dynamics simulations and X-ray diffraction to study the interaction of cortisone with model lipid membranes made of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) at drug concentrations from 0 ...