background: standard methods for the measurement of myocardial perfusion are invasive and require cardiac catheterization or the use of radioisotope dyes. the coronary sinus blood flow (csbf) is an appropriate criterion for the efficacy of myocardial perfusion. this study sought to measure csbf via transthoracic echocardiography (tte) in patients with acute myocardial infarction (ami) and to as...

In 19 children with Kawasaki disease without any cardiac sequelae the coronary sinus was cannulated via the femoral vein with a specially designed flow catheter and coronary sinus blood flow was measured by the continuous thermodilution method. There was a statistically significant positive correlation between coronary sinus blood flow and age, body surface area, and left ventricular mass, but ...

• Coronary flow measurements in the intact animal and in man have been based principally on the amount of the coronary sinus drainage. Two assumptions are involved in the use of the coronary sinus drainage as an index of total and of left ventricular coronary flow: (1) The coronary sinus flow is a fixed percentage of total coronary flow, and (2) it represents all or a constant portion of the ve...

The secretion of atrial natriuretic peptide by the heart is not simply the arterial-coronary sinus concentration difference times coronary blood flow, because only a small fraction of total coronary blood flow passes through the atria. We measured coronary sinus and arterial plasma atrial natriuretic factor (ANF) concentrations and blood flow to each part of the heart using the radioactive micr...

A 50-year-old man suffering from recurrent chest pain accompanied by transient ST-segment elevation developed spasm of the left anterior descending coronary artery after receiving ergonovine maleate. During spontaneous chest pain, thermodilution coronary sinus blood flow fell from 96 ml/min to 46 ml/min, while the coronary sinsu arteriovenous oxygen difference widened from 9.82 volumes percent ...

A 15-year-old girl was admitted for repair of partially unroofed coronary sinus syndrome. A preoperative echocardiographic study disclosed the dilated coronary sinus and a draining blood flow into the right atrium from both the left atrium and the end of the coronary sinus. At surgery, the distal portion of the coronary sinus roof was found to be absent. The defect was repaired through the coro...

Coronary sinus occlusion retards necrosis of ischemic myocardium. To test the hypothesis that coronary sinus occlusion induces retrograde venoarterial flow, the coronary arteriovenous pressure gradient and the coronary arterial oxygen saturation were measured distal to a left anterior descending coronary artery ligature in dogs. In parallel, we constructed a mathematical model of known coronary...

Ten patients with stable angina pectoris and obstructed coronary arteries (greater than 75% reduction in diameter) were studied before and during two periods of pacing, the second of which was preceded by sublingual administration of glyceryl trinitrate (mean dose 0.78 mg). Coronary sinus blood flow measurements and aortocoronary sinus blood sampling for metabolite determinations were carried o...

Coronary sinus blood flow was studied by the continuous thermodilution method in 13 subjects with normal coronary arteries and 14 patients with coronary artery disease during progressive elevation of the heart rate by atrial pacing. In 11 patients of the coronary group angina pectoris developed during pacing. In subjects with normal coronary arteries the coronary sinus blood flow rose proportio...

OBJECTIVE To evaluate the Coronary Flow Reserve in the Coronary Sinus through transesophageal Doppler echocardiography in normal subjects. METHODS We obtained technically adequate flow samples for analysis in 10 healthy volunteers (37+/-8 years, 5 men) with no history of heart or systemic disease and with mean left ventricular mass index by transthoracic echocardiography of 87+/-18 g/m2. Coro...