heart failure is a clinical syndrome characterized by the inability of the heart to provide nutrient supply to tissues. in 75% of cases, the underlying pathology causing heart failure in patients with cardiac death is coronary heart disease. a rabbit model of heart failure with coronary ligation was produced to mimic coronary heart disease in humans. after producing the model, two arteries and ...

objective(s): electrical inhomogeneity between ischemic and non ischemic myocardium is the basis of arrhythmia which occurs following coronary artery occlusion. the leakage of potassium from the ischemic region to the non ischemic region is very effective in the generation of these arrhythmias. the aim of this study is to research the effect of atp-dependent potassium (katp) channel blocker (gl...

Heart failure is a clinical syndrome characterized by the inability of the heart to provide nutrient supply to tissues. In 75% of cases, the underlying pathology causing heart failure in patients with cardiac death is coronary heart disease. A rabbit model of heart failure with coronary ligation was produced to mimic coronary heart disease in humans. After producing the model, two arteries ...

the purpose of the work presented here was to investigate endotheliumdependent relaxations in the rabbit coronary ligation model of heart failure. we investigated endothelium-dependent relaxations at the level of larger vessels (thoracic aorta and vena cava left renal artery and left renal vein lateral saphenous artery and lateral saphenous vein and finally central ear artery and marginal ear v...

Coronary aneurysms are typically seen in association with Kawasaki disease and only in rare instances, they are reported to be congenital or idiopathic. Here we report a case of a five year old boy who was found to have an idiopathic right coronary artery aneurysm. He presented with complaints of recurrent respiratory tract infections. His examination and investigations did not reveal any of th...

The purpose of this study was to evaluate the efficacy of time-controlled intermittent coronary sinus occlusion (ICSO) in preserving regional and global mechanical function during acute ischemia in an animal preparation without significant arterial collateral vessels. Seventeen (eight control, nine ICSO) swine heart preparations undergoing extracorporeal coronary perfusion in situ were subjecte...

It has been shown that the size of myocardial infarction in rats created by coronary ligation technique is not uniform, varying from 4% to 65%. We hypothesized that infarct size variability induced by coronary artery ligation might be caused by coronary artery branching pattern. Coronary artery angiography was performed in 50 normal Lewis rats and in chronic myocardial infarction models in whic...

Recently a potent anti-inflammatory effect of hydroalcoholic extract of the aerial parts of the sterile stems of Stachys inflata has been reported. This study examined whether hydroalcoholic extract isolated from aerial parts of non-flowering stems of Stachys inflata (standardized to contain 4.5% caffeic acid derivatives) reduce myocardial infarct size arising from coronary artery occlusion (30...

iatrogenic dissections of the ascending aorta are an uncommon and severe complication during cardiac catheterization. a 68-year-old female patient underwent diagnostic cardiac catheterization due to non-st-elevation myocardial infarction. during the procedure, a catheter-induced 360 • class i dissection of the right coronary artery occurred. the patient developed severe bradycardia, which was t...