Purpose Most of the inflammation in murine herpes simplex virus type 1 (HSV-1)-induced stromal keratitis (HSK) is due to exposure stress resulting from loss of corneal nerves and blink reflex. Corneal grafts often fail when placed on corneal beds with a history of HSK. We asked if corneal exposure contributes to the severe pathology of corneal grafts on HSV-1-infected corneal beds. Methods He...

citicoline is a natural substance with neuroprotective and repairing effects. it can also increase the phosphor metabolites in cerebral cortex. regarding the various effects of citicoline on central nervous system, this research aims at studying the effects of citicoline on the thiopental sodium anesthesia. six dogs were anesthetized by intravenous injection of 20 mg ∕ kg of 2.5% thiopental sod...

A series of direct photographic measurements of corneal reflex positions was taken to reconcile discrepant interpretations of the Hirschberg test. A value of 21 prism diopters per millimeter was obtained for the conversion factor relating ocular rotations to reflex displacement, valid over a range of 200 prism D. Quantitative interpretation of routine clinical photographs of strabismic patients...

An experimental study and mathematical analysis of the corneal reflex test was undertaken in spectacle wearers. In the experimental study, photographs were taken of the corneal reflex through spectacles and the conversion ratios determined as measured in degrees/mm. In the mathematical analysis, the magnification effect of the lens was elucidated by three methods: geometrical analysis; real mea...

PURPOSE To develop a mouse model of neurotrophic keratopathy by approaching the trigeminal nerve through the brain and to evaluate changes in corneal cell apoptosis and proliferation. METHODS Six- to 8-week-old male C57BL/6 mice underwent trigeminal stereotactic electrolysis (TSE) to destroy the ophthalmic branch of the trigeminal nerve. Clinical follow-up using biomicroscopy of the cornea wa...

The corneal and blink reflexes were evaluated in 20 normal subjects and in 30 patients with motor deficits secondary to unilateral hemispheral lesions of vascular origin. In the normal population there were no differences between subjects below and subjects above 50 years of age. In the patients the reflex evoked by electrical stimulation of the cornea of the clinically affected side was depres...

Blink reflex, corneal reflex, jaw reflex, exteroceptive suppression in masseter muscles and brainstem auditory evoked potentials were measured in 20 patients with Huntington's chorea and 12 controls. A significantly increased latency of the second component of the homolateral and heterolateral blink reflex was found in the patient group as compared with the controls. The other investigations re...