introduction: recurrent corneal erosion occurs when the wounded corneal epithelium failed to adhere to the underlying stroma. therefore, this work aimed to assess the effect of treatment of corneal injury using q- switched nd:yag laser.  method: twenty one new zealand male rabbits weighing 2-2.5 kg and 3 months old were classified into three main groups. the control group: did not received any ...

background: the aim of this study is to create an ex vivo model to examine the expression of two heat shock protein 70 (hsp70) family members, heat shock protein 72 (hsp72) and heat shock constitute protein 70 (hsc70), at the mrna and protein levels in differentiating corneal cells from air exposed limbal stem cells. materials and methods: limbal biopsies were cultured as explants on a cellular...

purpose : to report a case of recurrent corneal intrastromal cyst containing lymph fluid case report : a 13-year-old girl presented with recurrent cyst of the left cornea, which had been drained three years before, but had gradually recurred. the cyst was successfully drained. histologic examination, cytologic analysis, and protein electrophoresis were performed on the cyst fluid. histopatholog...

normal 0 false false false en-us x-none ar-sa background : the aim of this study was to determine the correlation between corneal hysteresis (ch) and the corneal resistance factor (crf), which are both novel methods of analyzing ocular rigidity/elasticity, and various corneal characteristics, mainly corneal volume in normal subjects. methods : this cross-sectional study included 500 normal eyes...

The transparent corneal stroma contains a population of corneal fibroblasts termed keratocytes, which are interspersed between the collagen lamellae. Under normal conditions, the keratocytes are quiescent and transparent. However, after corneal injury the keratocytes become activated and transform into backscattering wound-healing fibroblasts resulting in corneal opacification. At present, the ...

PURPOSE To demonstrate the constitutive expression and regulation of heparanase (heparan sulfate endoglycosidase) in the normal mouse eye and in mice intracorneally infected with Pseudomonas aeruginosa. METHODS Naïve (unimmunized) and immunized C57BL/6J mice were infected with P. aeruginosa, and corneal heparanase gene and protein expression were detected by semiquantitative RT-PCR and immuno...

PURPOSE Connective tissue growth factor (CTGF) has been linked to fibrosis in several tissues. In this study, the interactions between CTGF and transforming growth factor (TGF)-beta were assessed in human corneal fibroblasts, and the levels and location of CTGF protein and mRNA were measured during healing of excimer laser ablation wounds in rat corneas. METHODS Human corneal fibroblasts were...

We have identified a 52 kDa protein, which is a potent substrate for cholera toxin-dependent ADP-ribosylation, in the compound eye preparation of the fruit fly, Drosophila melanogaster. We find that the 52 kDa protein is a glycoprotein and a Ca2+ binder bearing a high content of leucine, serine and glycine. By microsequencing we determined its 13 N-terminal sequence, AYL*PIDLNQLAK, with the ast...

OBJECTIVE This study was undertaken to investigate the effects of recombinant human epidermal growth factor (rhEGF) and protein-free calf blood extract on corneal wound healing and neovascularization. MATERIALS AND METHODS An rabbit central corneal wound and neovascularization model was established in rabbits. One eye of each group was chosen randomly for topical administration of protein-fre...