purpose: to describe a case with a rare complication of posterior chamber intraocular lens (pc-iol) implantation in a patient who had undergone extracapsular cataract extraction (ecce) two years before case report: a 80-year-old diabetic woman presented with an exposed pc-iol in her left eye with a history of mechanical trauma. slit-lamp examination revealed an extruded pc-iol lied on the anter...

PURPOSE To report a case of corneal melting in a patient with fornix foreshortening being treated with reformulated generic diclofenac. METHODS Case report. RESULTS An asymptomatic 76-year old man presented with central corneal melting while being treated with reformulated generic diclofenac. This formulation did not contain the vitamin E derivative, tocophersolan, which has been felt to co...

BACKGROUND To report a case of spontaneous corneal melting in pregnancy. We reviewed the literature on corneal melting and the effect of pregnancy on cornea and collagen containing tissues. CASE PRESENTATION A 29-year-old woman who underwent radial keratotomy in both eyes followed by trabeculectomy in her left eye developed corneal melting in the same eye, in her seventh month of pregnancy. D...

The compounds benzyloxycarbonyl-L-leucyl-hydroxamate (Z-Leu-NHOH), phosphoryl-L-leucyl-L-phenylalanine (P-Leu-Phe) and 2-mercaptoacetyl-L-phenylalanyl-L-leucine (HSAc-Phe-Leu) strongly inhibit the activity of Pseudomonas elastase in vitro. The capacity of these inhibitors to prevent corneal melting and perforation due to the elastase was examined in rabbit eyes by intrastromal injections of ela...

INTRODUCTION Biomechanical changes in the cornea during pregnancy might lead to pathological conditions such as corneal perforation or melting. CASE PRESENTATION A 33-year-old Asian female who underwent penetrating keratoplasty in both eyes developed corneal melting in the right eye and marginal keratitis in the left eye in her fifth month of pregnancy. Marginal keratitis in the left eye imme...

OBJECTIVE UV-A/riboflavin cross-linking (CXL) of corneal collagen fibers is an established, highly promising therapy for corneal melting in physician-based ophthalmology. A prospective pilot study was conducted to demonstrate proof of principle of this novel method for the treatment of melting corneal ulcers in dogs and cats. PROCEDURES After obtaining owner consent, CXL was performed in thre...

Purpose: To demonstrate the effectiveness of UVA/riboflavin cross-linking (CXL) in the treatment of therapy resistant corneal melting of different etiology. Methods: This paper describes a series of four cases presenting severe ulcerative keratitis with infectious and noninfectious causes. In spite of intensive medical treatment, corneal melting did develop in all four eyes. CXL was performed t...

AIMS To estimate the incidence of corneal melting or necrotising keratitis in association with systemic disease in the Yorkshire Region and to determine the type and duration of the systemic association. METHODS In a prospective study, vigorous attempts were made to identify all patients presenting with newly diagnosed corneal melting over a 3 year period. RESULTS 27 patients were identifie...

PURPOSE To describe a new surgical approach for the tectonic reconstruction of the anterior ocular segment and the management of scleral and conjuctival melting. METHODS Case series of patients demonstrating anterior segment anomalies, such as scleral and conjunctival melting. The anterior stromal part of a pre-cut corneal graft for Descemet's stripping automated endothelial keratoplasty (DSA...