purpose : to review current knowledge about ocular effects of sulfur mustard (sm) and the associated histopathologic findings and clinical manifestations methods : literature review of medical articles (human and animal studies) was accomplished using pubmed, scopus and isi databases. a total of 274 relevant articles in english were retrieved and reviewed thoroughly. results : eyes are the most...

Background: The determination of common diseases in a region is a medical and health priority of that region. Ocular emergencies can cause permanent vision loss if they are not recognized and treated promptly.  Preserve vision of patients, We arranged this study  in Moradi hospital (Kerman, Iran), to estimate our regional situation. Materials and Methods: In this cross-sectional stud...

Patients hospitalized in the Intensive Care Unit (ICU) may present risk for corneal injury due to sedation or coma. This study aimed to estimate the incidence of corneal injuries; to identify the risk factors and to propose a risk prediction model for the development of corneal injury, in adult patients, in an intensive care unit of a public hospital. This is a one year, prospective cohort stud...

PURPOSE We attempted to develop a device for measuring electrical corneal resistance (CR) using corneal contact lens electrodes to quantitatively evaluate corneal injury in vivo. In the present study, full-thickness detachment of the corneal epithelium was induced by n-heptanol, and the feasibility of the quantitative evaluation of this injury by corneal contact lens electrodes was evaluated in...

BACKGROUND Wound healing of the endothelium occurs through cell enlargement and migration. However, the peripheral corneal endothelium may act as a cell resource for the recovery of corneal endothelium in endothelial injury. AIM To investigate the recovery process of corneal endothelial cells (CECs) from corneal endothelial injury. METHODS Three patients with unilateral chemical eye injurie...

BACKGROUND In our clinical experience we discovered that EEG band power may be correlated with corneal nerve injury in retinoblastoma patients. This study aimed to investigate biomarkers obtained from electroencephalography (EEG) recordings to reflect corneal nerve injury in retinoblastoma patients. MATERIAL AND METHODS Our study included 20 retinoblastoma patients treated at the Department of ...

Limbal stem cell (LSC) on the basal layer of cornea plays an important role in the epithelial repair after corneal injury as it can proliferate, differentiate and migrate into injury sites under the direction of cytokines. This study explored the signaling pathway and cellular mechanism between corneal epithelial cells LSC, on a mouse model with mechanic corneal injury. Ipsilateral corneal mech...

PURPOSE To determine if aquaporin-1 expression is decreased in human and mouse corneal endothelial dysfunction. METHODS Immunohistochemistry with anti-aquaporin 1 antibody and confocal microscopy were used to study a case series of human corneal specimens, and a mouse model of corneal endothelial injury was created with injection of sterile hot water into the anterior chamber with a 33 gauge ...