نتایج جستجو برای: copy number variations

تعداد نتایج: 1355626  

Journal: :Neurological Sciences 2016

Journal: :Cytogenetic and Genome Research 2008

Journal: :The American Journal of Human Genetics 2015

Journal: :The American Journal of Human Genetics 2007

Journal: :Cytogenetic and genome research 2008
H Riethman

Copy number variation is a defining characteristic of human subtelomeres. Human subtelomeric segmental duplication regions ('Subtelomeric Repeats') comprise about 25% of the most distal 500 kb and 80% of the most distal 100 kb in human DNA. Huge allelic disparities seen in subtelomeric DNA sequence content and organization are postulated to have an impact on the dosage of transcripts embedded w...

Journal: :hepatitis monthly 0
sharareh kamfar department of molecular medicine and genetics, school of medicine, hamadan university of medical sciences, hamadan, ir iran; research center for molecular medicine, hamadan university of medical sciences, hamadan, ir iran seyed moayed alavian baqiyatallah research center for gastroenterology and liver diseases (brcgl), baqiyatallah university of medical sciences, tehran, ir iran; middle east liver diseases (meld) center, tehran, ir iran massoud houshmand department of medical genetics, national institute for genetic engineering and biotechnology, tehran, ir iran reza yadegarazari shohada hospital of harsin, kermanshah university of medical sciences, kermanshah, ir iran bahram seifi zarei school of medicine, shahid beheshti hospital, hamadan university of medical sciences, hamadan, ir iran alireza khalaj obesity treatment center, department of surgery, shahed university, tehran, ir iran

results the relative expression of mtdna copy number was 3.7 fold higher in nafld patients than healthy controls (p < 0.0001). the results remained significant after adjustment for age, bmi, and gender (p = 0.02). in addition, the mtdna copy number was 4.3 (p < 0.0001) and 3.2-fold (p < 0.0001) higher in nonalcoholic fatty liver (nafl) and non-alcoholic steatohepatitis (nash) patients than heal...

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