how to cite this article: kheradmand z, yarali b, zare a, pourpak z, shams s, ashrafi mr. comparison of serum zinc and copper levels in children and adolescents with intractable and controlled epilepsy. iran j child neurol. 2014; 8(3):49-54.   abstract objective trace elements such as zinc and copper have physiological effects on neuronal excitability that may play a role in the etiology of int...

objective:   intractable epilepsy is a serious neurologic problem with different etiologies. decreased levels of pyridoxal phosphate in central spinal fluid level of patients with intractable epilepsy due to pyridoxine dependency epilepsy were reported. the aim of this study was to compare plasma pyridoxal 5´-phosphate level in patients with intractable and controlled epilepsy. materials   &   ...

Introduction: Celiac disease can be associated with other diseases, including neurological disorders. In this study, the relationship between celiac disease and refractory epilepsy was evaluated in patients who were referred to Imam Khomeini Hospital in Urmia. Methods: In this cross-sectional study, patients with refractory epilepsy who were referred to the neurology clinic of Imam Khomeini Ho...

objective epilepsy occurs with a yearly incidence of 40 per 100,000 children, of which more than 25% are resistant to drug therapy. epilepsy may occur in autoimmune diseases like lupus, celiac disease and myasthenia gravis. in this study, the relationship between celiac disease and refractory epilepsy was evaluated in children with idiopathic epilepsy. material & methods hundred-fifty-five chil...

Epilepsy is one of the most important diseases of nervous system that involves 0.5-1% of the population. In spite of new developments in antiepileptic drugs, between 20-30% of epileptic patients can not be controlled and even those who are controlled with antiepileptic drugs suffer from their adverse events. Epileptic patients have different challenges in relation to the disease and its medicat...

Background: Epilepsy is the second common neurologic disorder. Although many antiepileptic drugs have been formulated to control the seizures, but not all seizures have been controlled by them. Uncontrolled epilepsy can actually reduce the patients’ quality of life. Objectives: Identifying the proportion of adult intractable epilepsy among epileptic patients in an area in the North East o...

background: epilepsy is the second common neurologic disorder. although many antiepileptic drugs have been formulated to control the seizures, but not all seizures have been controlled by them. uncontrolled epilepsy can actually reduce the patients’ quality of life. objectives: identifying the proportion of adult intractable epilepsy among epileptic patients in an area in the north east of iran...

BACKGROUND: Epilepsy is a neurological disorder. Its incidence in Indonesia was 700,000–1,400,000 cases and 40–50% occurred children. About 30–40% of children had uncontrolled seizures. Biomarkers are needed to assess the prognostic value patients with epilepsy. Malondialdehyde (MDA) brain-derived neurotrophic factor (BDNF) one biomarkers related epilepsy see effect oxidative stress neuroplasti...

OBJECTIVE Cortical excitability differs between treatment responders and nonresponders in new-onset epilepsy. Moreover, during the first 3 years of epilepsy, cortical excitability becomes more abnormal in nonresponders but normalizes in responders. Here, we study chronic active epilepsy, to examine whether cortical excitability continues to evolve over time, in association with epilepsy duratio...

OBJECTIVE Intractable epilepsy is a serious neurologic problem with different etiologies. Decreased levels of pyridoxal phosphate in cerebral spinal fluid of patients with intractable epilepsy due to pyridoxine dependency epilepsy are reported. The aim of this study was to compare plasma pyridoxal 5´-phosphate level in patients with intractable and controlled epilepsy. MATERIALS & METHODS Thi...