lipoprotein-associated phospholipase a2 (lp-pla2) is produced by inflammatory cells, bound to ldl and other lipoproteins, and hydrolyzes oxidized phospholipids in ldl. type 2 diabetes is the most common form of diabetes some investigations show the association of lipoprotein-associated phospholipase a2 mass and activity with the incidence of cardiovascular disease (cvd) in populations with high...

background: opiate is used in patient-controlled intravenous analgesia pumps (pcia) for controlling pain in post-surgical patients.other drugs are remarkably added to opioid pumps to enhance quality, lengthen analgesia, and reduce side effects. lidocaine, a local anesthetic which inhibits sodium channels, has anesthetic and analgesic effects when injected locally or intravenously. the objective...

background: deliberate hypotension is a strategy that reduces intraoperative bleeding and increases the speed of surgery in otolaryngology procedures. magnesium (mg) sulfate is a vasodilator agent that reduces intraoperative hypnotic requirements and in combination with analgesic agents, it reduces intraoperative and postoperative pain. in this study we evaluated the use of intravenous mg sulfa...

pituitary suppression by depot gnrh agonist may be excessive for ovarian stimulation. this study compares the efficacy of a single half-dose depot triptorelin and reduced-dose daily buserelin in a long protocol icsi/et. methods: a total of 182 patients were randomized into two groups using sealed envelopes. pituitary desensitization was obtained in group 1 (91 patients) with half-dose (1.87 mg)...

microparticles offer various significant advantages as drug delivery systems, including: (i) an effective protection of the encapsulated active agent against (e.g. enzymatic) degradation, (ii) the possibility to accurately control the release rate of the incorporated drug over periods of hours to months, (iii) an easy administration (compared to alternative parenteral controlled release dosage ...

background: there are two types of primary dysmenorrhea (spasmodic and congestive) which differ from each other in terms of the time of menstrual cycle outbreak, pain quality and other symptoms. the present study aimed to determine the effect of acupressure at the sanyinjiao point (sp-6) on severity of menstrual symptoms (primary outcome) and the duration of resting time as well as the number o...

conclusions these findings indicate the usefulness of pca compared to the routine methods on pain relief after operation.therefore this method can be recommended to alleviate postoperative pain. background unrelieved pain after surgery can lead to increased postoperative complications, prolonged hospital stay and delayed recovery. patient-controlled analgesia (pca) has emerged as a standard tec...

thymol, an important and advantageous component of many essential oils, has been applied as an antimicrobial agent in animals. to increase the duration of action of this compound in ruminants, it was decided here to prepare a controlled release carrier for thymol. hydroxy propyl methyl cellulose (hpmc) and ethyl cellulose (ec) were used as the matrix polymer here. mixtures of thymol with eight ...

conclusions both pca techniques provided effective pain scores (< 3) after cardiac surgery; but generally, pca-paracetamol infusion has a better analgesic effect. results the trend of pain scores did not have any significantly difference between group r and group p except for hour 8 and hour 18 after surgery that vas was significantly lower in group p than group r (p = 0.031, p = 0.023, respect...