Background: Various kinds of sensitizers are administrated foralopecia areata treatment. The aim of this study was to evaluatetreatment response to Dinitrochlorobenzene (DNCB) in alopeciaareata patients.Method: In this study, 117 patients were treated with DNCBunder a specific checklist. All patients were sensitized with a 2%DNCB and then treated with ascending DNCB concentrations(0.001%-2%). R...

INTRODUCTION Contact dermatitis is a relatively common dermatosis reported among several population groups from all around the globe. However, the data from Kuwait is unavailable. Patch tests are essential for the diagnosis of contact sensitization. AIM To determine a relative frequency and pattern of sensitizers to different allergens in patients of suspected contact dermatitis in Kuwait and...

INTRODUCTION Glycerin is a rare sensitizer and is widely used for cosmetics, medicine, and food for its stable, nontoxic properties. We report on a patient with generalized urticarial eruptions who had contact urticaria syndrome caused by glycerin enema. Our case suggests that glycerin can be a cause of contact urticaria syndrome and even anaphylaxis, although allergic reactions to glycerin are...

In earlier observations with the picryl system, it was concluded that contact sensitivity was a form of delayed (cellular) hypersensitivity to conjugates of sensitizer with autologous proteins indistinguishable in its immunological mechanism from other classical forms of delayed hypersensitivity to proteins. This conclusion has been confirmed and extended with the picryl and chlorbenzoyl chlori...

BACKGROUND Allergic contact dermatitis (ACD) represents a severe health problem with increasing worldwide prevalence. It is a T cell-mediated skin disease induced by protein-reactive organic and inorganic chemicals. A key feature of contact allergens is their ability to trigger an innate immune response that leads to skin inflammation. Previous evidence from the mouse contact hypersensitivity (...

Sir, Recalcitrant warts remains a major therapeutic challenge for patients as well as for dermatologists, and an effective, painless, atraumatic treatment modality is needed world-wide. Topical immunotherapy has for years been used with some success in the treatment of resistant warts (1). Dinitrochlorobenzene (DNCB) was the ®rst contact sensitizer to be used but diphenylcyclopropenone (DCP) is...

Background: Hand eczema is one of the most common dermatological disorders caused by various exogenous and endogenous factors. The condition that is frequently multifactorial, usually disabling or distressing to the sufferer, and often difficult to treat Objectives: To study the clinical types of contact allergic dermatitis of hands and to correlate the allergens related to allergic contact der...

Temporary tattoos, especially those that contain black dyes, have become rampant among teenagers in recent years. Most of these tattoos, in addition to hair dyes include paraphenylenediamine (PPD). PPD is a well-known skin sensitizer, which causes allergic contact dermatitis. Allergic contact dermatitis skin lesions from PPD are mostly seen as erythema multiforme-like eruption, a bullous contac...