conclusions unexpected complications may be seen during the course of cchf. patients must be closely followed up. case presentation a 49-year-old male dealing with livestock husbandry was admitted to ankara training and research hospital with three days of complaints including fever, malaise, headache, myalgia, nausea, vomiting, diarrhoea and hematuria. laboratory findings (thrombocytopenia and...

introduction : this study was aimed to investigate the effects of risk factors, and environmental and climatic factors a ffecting the occurrence of crimean-congo hemorrhagic fever (cchf) in iran. we used temporal modeling to predict the future occurrence of the disease in the country . methods : we analyzed the data of 165 cchf patients from all over iran (e xcept the districts zabol and zaheda...

To confirm the presence of Crimean-Congo hemorrhagic fever in Sudan, we tested serum of 8 patients with hemorrhagic fever in a rural hospital in 2008. Reverse transcription-PCR identified Crimean-Congo hemorrhagic fever virus. Its identification as group III lineage indicated links to virus strains from South Africa, Mauritania, and Nigeria.

results primary, secondary, and 3d structure of cchfv gn were obtained and pcr reaction with m13 forward and reverse primers confirmed the generation of recombinant bacmid dna harboring gn coding region under polyhedron promoter. conclusions characterization of the detailed structure of cchfv gn by bioinformatics software provides the basis for development of new experiments and construction of...

conclusions the viral load in patients who suffer from cchf has a direct significant correlation with disease severity. viral load above 8.6 × 105 copies/ml on the first day of admission is a predictor of severe cchf. background crimean-congo hemorrhagic fever (cchf) is an endemic disease in south eastern of iran, especially in sistan and baluchestan province. cchf is a potentially fatal diseas...

Crimean-Congo hemorrhagic fever is a tick-borne viral disease reported from more than 30 countries in Africa, Asia, South-East Europe, and the Middle East. The majority of human cases are workers in livestock industry, agriculture, slaughterhouses, and veterinary practice. Nosocomial transmission is also well described. Clinical manifestations are nonspecific and symptoms typically include high...

1. Grard G, Drexler JF, Fair J, Muyembe JJ, Wolfe ND, Drosten C, et al. Re-emergence of Crimean-Congo hemorrhagic fever virus in Central Africa. PLoS Negl Trop Dis. 2011;5:e1350. http://dx.doi. org/10.1371/journal.pntd.0001350 2. Mild M, Simon M, Albert J, Mirazimi A. Towards an understanding of the migration of Crimean-Congo hemorrhagic fever virus. J Gen Virol. 2010;91:199–207. http://dx.doi....

conclusions this study showed that this novel one-step rrt-pcr assay is a rapid, reliable, repeatable, specific, sensitive, and simple tool for the detection of the cchf virus. results from a total of 75 suspected serum samples, 42 were confirmed to be positive for cchf virus, with no false-positives detected by the sequencing results. after 40 amplification cycles, the melting curve analysis r...

368 www.thelancet.com/infection Vol 17 April 2017 1 Haider S, Hassali AM, Iqbal Q, et al. Crimean-Congo haemorrhagic fever in Pakistan. Lancet Infect Dis 2016; 16: 1333. 2 Müller MA, Devignot S, Lattwein E, et al. Evidence for widespread infection of African bats with Crimean-Congo hemorrhagic fever-like viruses. Sci Rep 2016; 6: 26637. 3 Mourya DT, Yadav PD, Shete AM, et al. Cross-sectional se...