background and aims: crimean-congo hemorrhagic fever (cchf) is a fatal viral disease that occurs in approximately 30 countries. it has the most extensive geographic range among the tick-borne viruses that affect human health. cchf viruses have a tripartite rna genome consisting of large (l), medium (m) and small (s) segments. this study was undertaken to determine the genetic relationship of cc...

background crimean-congo hemorrhagic fever (cchf) is a tick-borne disease caused by arbovirus which can be transmitted to human by several routes. tick bite and living in a rural area have been the most common factors for inception of cchf in adults and children in studies reported from iran. objectives this study was conducted to detect the disease acquisition routes among children with confir...

southeast of iran is an endemic area for malaria and crimean-congo hemorrhagic fever ( cchf). in 1999, we faced with an outbreak of cchf in sistan and baluchistan province, in the border of paki­stan and afghanistan. the most cases of malaria in iran are also reported from this area. this arti­cle presents a 17-year- old woman who admitted to our hospital because of acute fever, head­ache, epis...

conclusions continuous training is necessary to improve the knowledge and awareness of the highest-risk groups with regard to the transmission modes, prevention, symptoms, and treatment of this disease. objectives this study is a retrospective descriptive survey based on data collected from the health center of khuzestan province, iran, during 1999 - 2015. patients and methods patients with sym...

OBJECTIVE Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with a high mortality rate. Despite increasing knowledge about hemorrhagic fever viruses, little is known about the pathogenesis of Crimean-Congo hemorrhagic fever. In this study, we measured serum adenosine deaminase and xanthine oxidase levels in Crimean-Congo hemorrhagic fever patients. METHODS Serum adenosine de...

since 1999, many cases of crimean-congo hemorrhagic fever have been reported from different parts of iran. this study intended to define cchf seroprevalence, incidence rates, and the most important risks in sistan- baluchestan province, iran. using cluster sampling with probability proportional to size, 310 subjects were selected from various districts of zahedan and zabol in the northern part ...

background: crimean-congo hemorrhagic fever (cchf) is a disease characterized by serious course, including acute viral fever, ecchymosis, thrombocytopenia, liver dysfunction and high rate of mortality. hypoxia inducible factor-1α (hif-1α) and vascular endothelial growth factor-a (vegf-a) play an important role both in the inflamma­tory process and plasma leakage. the aim of this study was to de...

case presentation this article presents a 56-year-old woman from guilan province, the north of iran and the southern coast of the caspian sea, who admitted to the hospital with acute fever, severe headache, thrombocytopenia, anemia, epigastric pain, myalgia, nausea and vomiting. conclusions we recognized that the case was co-infected by cchf and leptospirosis. introduction infectious diseases a...

BACKGROUND & OBJECTIVES Crimean - Congo hemorrhagic fever is an acute viral hemorrhagic fever with considerable mortality. Despite increasing knowledge about hemorrhagic fever viruses, the pathogenesis of Crimean -Congo hemorrhagic fever and causes of death were not well described. We aimed to evaluate whether there were electrocardiographic parameters designating mortality among these patients...