Congenital complete heart block can occur in sibs with and without associated congenital heart defects.' This has been associated with different histological changes, but the ultimate cause has remained obscure. Recently there have been reports of an association between congenital heart block and maternal systemic lupus erythematosus.24 This report concerns two sisters with congenital complete ...

Congenital Heart Block (CHB) is the most serious complication of neonatal lupus erythematosus. Transplasental transfer of maternal anti SSA/Ro or antiSSB/La antibodies around 12th week of gestation is associated with development of CHB. This may lead to inflammation, fibrosis and scarring of fetal conduction system in the early second trimester. Different degrees of atrioventricular (AV) block ...

Although congenital complete heart block is well recognized and has been fully reviewed, congenital partial heart block appears to be much more unusual. Howevev, a survey shows that several such cases have been described in America, but we have found only four cases recorded from this country. Whipham (1915) reported two, and Fleming and Stevenson (1928) gave an account of an eight-year-old gir...