A part of the immune system that improves (complements) the ability of antibodies and phagocytic cells to clear microorganisms and injured cells from an organism, attacks the pathogen's cell membrane, and encourages inflammation called complement system. It is main part of immune system. Over thirty proteins and protein pieces compose the complement system, including cell membrane receptors, an...

multiple sclerosis (ms) is a complex, demyelinating disease of the central nervous system (cns) with variable phenotypic presentations, while guillain-barre syndrome (gbs) is the prototypic acute inflammatory disorder that affects the peripheral nervous system. myasthenia gravis (mg) is a t cell dependent and antibody mediated autoimmune disease. although it has been shown that complement plays...

angioedema is characterized by recurrent, circumscribed, solitary or multiple subcutaneous and mucosal swelling, involving the extremities, face, larynx, bowel wall. angioedema is due to hereditary or acquired varieties of c1 esterase inhibitor (c1inh) deficiency. a case of atypical acquired angioedema in a 49-year old man, responding favourably to cinnarizine and alcohol abstinence, is present...

introduction: mcp (membrane cofactor protein or cd46) is a complement regulatory proteins (crps), which is present in most of body cell membranes (except erythrocytes), and also in most biologycal body fliuds. due to the important role of this protein in the complement system, specially in fertility, the aim of this study was to determine and isolate this protein in human seminal plasma. materi...

background: occupational exposure to cotton dust, fibers, metal fumes and different chemicals used in the apparel manufacturing industries cause a wide range of physical and psychological health problems in the garment workers that may also affect their immune function. objective: to assess the immune system function in garment workers. methods: a total of 45 workers of a garment factory, and 4...

background and objectives: complement proteins are some of the most important plasma proteins of the innate immune system. impaired immune function is reported in subjects who are iron deficient, and there are documents that these patients are prone to infection. this study was conducted to show whether serum c3 and c4 complement change in adult nonpregnant female with iron deficient anemia or ...

Background: Idiopathic anterior uveitis is an anterior segment inflammation in which a detailed medical history, general and ocular physical examination is not associated with any defined clinical syndrome. Alterations in immune system parameters have been reported in patients with idiopathic posterior uveitis; however no data on the role of immune system in idiopathic anterior uveitis has yet ...

Background and Objectives: Complement proteins are some of the most important plasma proteins of the innate immune system. Impaired immune function is reported in subjects who are iron deficient, and there are documents that these patients are prone to infection. This study was conducted to show whether serum C3 and C4 complement change in adult nonpregnant female with iron deficient anemia or ...

Background: Inappropriate activation or blockage of the inhibition of complement system could cause tissue damages in autoimmune diseases particularly rheumatoid arthritis (RA). Defect in complement component regulation may cause damages to tissues, on the other hand, or the damaged tissue might affect the unnecessary activation of complement components.   Objective: To investigate the expressi...