BACKGROUND Physicians consider ease of use, satisfaction, and preferences when prescribing an inhaler device. These factors may impact appropriate usage and compliance. METHODS The objectives were to quantify the relative importance of inhaler attributes in patients currently using Combivent Respimat by eliciting preferences for performance and convenience attributes assessed by items in the ...

BACKGROUND Routine addition of ipratropium bromide to beta-agonist therapy in acute asthma is of uncertain benefit. OBJECTIVE This study was carried out to evaluate: (1) whether nebulized ipratropium (0.5 mg) plus salbutamol (2.5 mg) (Combivent) confers additional bronchodilation over nebulized salbutamol (2.5 mg) alone in patients with acute asthma and (2) whether adjustment for prognostic i...

The propellant-free Combivent Respimat Soft Mist Inhaler (CVT-R) was developed to replace the chlorofluorocarbon-propelled Combivent metered-dose inhaler (CVT-MDI). This steady-state pharmacokinetic (PK) substudy evaluated drug lung-delivery efficiency, using data from two phase III safety and efficacy trials. PK parameters were obtained from well-controlled population PK analyses. Area under t...

A randomized, double-blind, crossover trial was designed to compare the acute effects of Combivent and salbutamol on spirometric parameters in patients with moderate to severe asthma. Nineteen patients with a mean baseline forced expiratory volume in 1 sec. (FEV]) less than 65% predicted, were randomized on two separate days to receive two puffs of salbutamol (200 µg) or two puffs of Combiv...

a randomized, double-blind, crossover trial was designed to compare the acute effects of combivent and salbutamol on spirometric parameters in patients with moderate to severe asthma. nineteen patients with a mean baseline forced expiratory volume in 1 sec. (fev]) less than 65% predicted, were randomized on two separate days to receive two puffs of salbutamol (200 µg) or two puffs of combivent ...

en-bloc resection, and an end-to-end anastomosis was performed. The patient had an uneventful recovery, except for a late wound infection. She was discharged after 5 days. A 50-year-old woman presented with a 24-hour history of increasing pain in the left lower quadrant of the abdomen with fever (38.2 ° C) and general discomfort. She had a medical history of obesity, an abdominoplasty and asthm...

burden of COPD and that they address any demographic disparities in patients’ use of resources. These data would help clinicians and other health care professionals in developing disease-management programs that best suit a specific population. Bronchodilators are the mainstay for managing the symptoms of COPD. They may be prescribed on an as-needed basis at early stages of disease, but typical...

Case Report A 31 year female presented to the emergency department with rapid onset of blurring of vision, dizziness, and nausea. Examination showed a painless, fixed, dilated left pupil. Neurological examination was otherwise normal. There was no history of headache or trauma. MRI brain was reported as normal. Full blood count, electrolytes, serum glucose, and inflammatory markers were also no...