background colorectal cancer (crc) is one of the most common cancers worldwide which is not extensively researched in iran. objectives the present study aims to investigate the epidemiologic characteristics of crc in patients referred to selected hospitals of tehran university of medical sciences. patients and methods in this descriptive-analytic study 218 patients with colorectal cancer were i...

 Background: Gastric and colorectal adenocarcinoma are the second and the fifth most common cancers in Iran, respectively. Expression of cytokeratin 7 (CK7) is established in most malignancies including gastric and colorectal adenocarcinoma. Demonstration of Ck7 could be related to prognostic factors and help to the better management of the patients. The objective of our study was to evalu...

background: the oncologic behavior of mucinous adenocarcinoma (ma) of colorectal differs from non-mucinous adenocarcinoma (nma). ma is more advanced at diagnosis and has a poorer prognosis than nma. we aimed to evaluate prognostic factors and survival rate in patients with ma compared with nma in western iran. methods: during 2008-2015 in a retrospective study, 83 patients with crc referred to ...

background: gastric and colorectal adenocarcinoma are the second and the fifth most common cancers in iran, respectively. expression of cytokeratin 7 (ck7) is established in most malignancies including gastric and colorectal adenocarcinoma. demonstration of ck7 could be related to prognostic factors and help to the better management of the patients. the objective of our study was to evaluate th...

the tp53 tumor suppressor gene plays important roles in genomic stability. a common polymorphism at codon 72 of tp53 gene has been associated with increased risk for many human cancers. the p53 protein is expressed in colorectal cancer, but the reported prevalence of its expression varies widely. in the present study, the p53 protein expression in different genotypes of its codon 72 , was inves...

background: mucinous adenocarcinoma colorectal cancer present at a more colorectal advanced stage of disease and showe a poorer prognosis than those with other types of carcinoma. the purpose of the present study was to clarify the clinicopathological characteristics of mucinous colorectal carcinoma in the iranian population. methods: 110 patients with mucinous adenocarcinoma were selected from...

b a c k g r o u n d  & aim: it is very helpful to classify and predict the clinical  category  of a sample based  on  its  gene  expression  profile.  this  study  was  conducted  to predict  tissues  of colorectal adenoma,  adenocarcinoma,  and  paired  normal  in  colon  based  on  microarray  data  using  nearest shrunken centroid method. methods   &  materials:    in  this  study,   the  co...

background: colorectal adenocarcinoma is one of the most prevalent and treatable malignancies of the gastrointestinal tract. pattern of expression of the p53, p21, p16, e-cadherin and |î²|-catenin proteins are shown to be related to the prognosis of this malignancy. we aimed to compare the pattern of expression of these proteins in tumoral and nontumoral mucosal cells of cancer and on-cancer pa...

Colorectal cancer is one of the most common types of cancer and has a high mortality rate, making accurate prediction of clinical prognosis an important concern. This study sought to investigate the expression of two proteins, MMP-11 and VEGF-C, in colorectal adenocarcinoma tissues to provide options for better tumor detection. The correlation of the expression of these proteins with the clinic...