نتایج جستجو برای: colchicum kurdicum
تعداد نتایج: 228 فیلتر نتایج به سال:
Background and objectives: Colchicum kurdicum (Bornm.) Stef. is a flowering perennial monocotyledon plant that has many important bioactive compounds especially colchicine and colchicine derivatives. In this study, the ultrasound-assisted acidic-solvent extraction method coupled with response-surface method was presented as the successful method for large scale extract...
Background and purpose: Colchicum kurdicum (Bornm.) Stef. is a monocotyledon plant which is endemic to Iran. The corm and seeds of this plant have some bioactive compounds, especially tropolone alkaloids that are used in treatment of inflammations, rheumatoid arthritis, gout, joint pains, and cancers. This study aimed at optimization of colchicine extraction from the corms of C. kurdicum and ev...
An in-house strategy to dereplicate colchicinoid alkaloids was recently developed by our team. It aimed at quickly identifying Colchicum constituents using LC-MS (liquid chromatography-mass spectroscopy) and LC-UV/Vis PDA (liquid chromatography-ultraviolet/ visible photodiode array) techniques. In this project, our goal was to validate the developed method through analysing the alkaloid-rich fr...
As a part of a project designed to investigate Colchicum species in Jordan, the chemical constituents of Colchicum crocifolium Boiss. (Colchicaceae) were investigated using LC-MS and LC-UV/Vis PDA. A decision tree for working with colchicinods has been developed by incorporating data from LC-UV/PDA and LC-MS. This dereplication strategy draws upon the UV/PDA spectra to classify compounds into o...
PURPOSE Cancer is a long process that leads the organism to death and is associated with the normal cells acquiring the ability to divide permanently. Nowadays, the use of natural products in cancer therapy has a great importance. In addition, working with plants that are endemic to Turkey and determining the biological activities of these plant extracts, is extremely important due to the poten...
گونه‌هایLinum punctatum subsp. kurdicum و Ranunculus damascenus برای اولین بار از ایران گزارش می‌گردند. گونه Linum punctatum subsp. kurdicum از مناطق مرتفع واقع در خوی و پیرانشهر از آذربایجان جمع آوری شده گونه فوق در فلور ترکیه تحت نام Linum pycnophyllum subsp. kurdicum از وان ترکیه گزارش شده است. گونه Ranunculus damascenus از منطقه بانه واقع در استان کردستان و هم مرز با کشور عراق جمع آوری ش...
As part of our continuing investigation of Jordanian Colchicum species, the biologically active components of Colchicum brachyphyllum were pursued. Using bioactivity-directed fractionation, nine colchicinoids were isolated and characterized. One of these has a novel ring system, to which we have ascribed the trivial name (+)-demecolcinone (9), and it represents the first naturally occurring dex...
A 39-year-old man was admitted to hospital because of vomiting and diarrhoea. He had developed cardiomyopathy of unknown cause a decade earlier that was managed with diuretics and an angiotensin-converting enzyme inhibitor. Two years thereafter, insulindependent diabetes mellitus appeared. His HbA1c was controlled at 7.5%. Two weeks prior to admission, he developed a burning pain in both feet. ...
A 62-year-old male died of colchicine poisoning after accidental ingestion of Colchicum autumnale (meadow saffron). He ate a salad of plant with green leaves regarded as wild garlic (Allium ursinum). A few hours later he developed symptoms of gastroenteritis and was admitted to hospital. In spite of gastric lavage, activated charcoal and supportive measures, multi-organ system failure developed...
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