نتایج جستجو برای: coding rnas
تعداد نتایج: 150815 فیلتر نتایج به سال:
lncrnaها (long non-coding rnas)، رونوشتهای غیر کد کنندهی پروتئین با طول بلندتر از 200 نوکلئوتید هستند که از طریق ساختار مولکولی ویژهی خود، با سایر مولکولها در میانکنش بوده و از این طریق بر شماری از فرایندهای مهم سلولی تاثیرگذار هستند. بررسی کارکردهای lncrna در مسیرهای متنوع سلولی، به نحو گسترده مورد مطالعه قرار گرفته است. این مولکولها به شکل طبیعی در انواع سلولها بیان میشوند، اما بیان ک...
rna های غیرکدکننده شامل rna های غیرکدکننده ی بلند (long non-coding rnas) و micrornas در سال های اخیر در سرطان زایی بسیار مورد توجه قرار گرفته است. رونوشت های lncrnas از طریق دخالت در فرآیند هایی چون تنظیم پرتوانی سلول ها? تنظیم پیرایش های متناوب و سایر فرآیندهای مهم زیستی? در تنظیم پیچیدگی موجودات درگیر می باشند.احتمالا بیان lincrna-ror و واریانت های b21 وa1 با تومورزایی در ارتباط می باشند که ا...
lncrnas (long non-coding rnas) are responsible to control the degradation process, rna stability, orchestration, inhibition, transcription and histone modification etc. these rnas have been termed as the key agents of several mechanisms such as development, organogenesis and regeneration of damaged tissues etc. they interact with a number of partner molecules either protein, rnas or dnas and co...
Background: Ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. Various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. However, the aim of this review was to investigate the role of long non-co...
background: ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. however, the aim of this review was to investigate the role of long n...
messenger rnas may be targeted by short 19-27 nt rnas generally called small none-coding rnas (snrnas), the role of mirnas among other snrnas has been more studied and is well known. many researches show that all compartments of risc, proteins and mirnas take part in this wide range of regulatory impacts. ago protein homologs plus mirnas and target mrnas form a silencing complex in p-bodies whi...
Background:Long non-coding RNAs, as a big part of non-coding RNAs, are considered functionally more than past. These transcripts could be involved in carcinogenesis. SNHG6, as a long non-coding RNA, has been reported to be expressed more in colorectal cancer tissues than non-cancerous ones. Colorectal cancer as a malignancy needs fast prognostic and diagnostic methods for well...
Stem cells are a good alternative for regenerative medicine because of their characteristics such as self-renewal and differentiation potential. They are classified into different types of stem cells including embryonic stem cells, induced pluripotent stem cells, multipotent stem cells, and ultimately uni-potent stem cells. Mesenchymal stem cells extracted from adult tissues. Due to the lack of...
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