نتایج جستجو برای: coding rna
تعداد نتایج: 359041 فیلتر نتایج به سال:
breast carcinoma is the major cause of cancer-related death in women. the incidence of this carcinoma is rising and there are many attempts to decrease this problem. the aim of this study was detection of full-length cytokeratin 19 (ck19) mrna, in peripheral blood and tissue of breast cancer patients in early stage of cancer. in this study, rt-pcr (reverse transcriptase-polymerase chain reactio...
rna های غیرکدکننده شامل rna های غیرکدکننده ی بلند (long non-coding rnas) و micrornas در سال های اخیر در سرطان زایی بسیار مورد توجه قرار گرفته است. رونوشت های lncrnas از طریق دخالت در فرآیند هایی چون تنظیم پرتوانی سلول ها? تنظیم پیرایش های متناوب و سایر فرآیندهای مهم زیستی? در تنظیم پیچیدگی موجودات درگیر می باشند.احتمالا بیان lincrna-ror و واریانت های b21 وa1 با تومورزایی در ارتباط می باشند که ا...
In this study the cis and trans regulatory effect of long non-coding genes (lncRNA) on the expression of genes in fish infected by Viral hemorrhagic septicemia virus (VHS) was investigated using RNA-seq technology. At the end of experimental period (the thirty fifth day), total RNA was extracted from spleen tissue (group treated with virus) and physiological serum (control group) was used to pr...
objective(s): similar characteristics of molecular pathways between cellular reprogramming events and tumorigenesis have been accentuated in recent years. reprogramming-related transcription factors, also known as yamanaka factors (oct4, sox2, klf4, and c-myc), are also well-known oncogenes promoting cancer initiation, progression, and cellular transformation into cancer stem cells. long non-co...
Summary: SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA associated with cancer pathogenesis. It contributes to a variety of cellular functions and recent evidence propounds its association with autophagy process. It has been showed that SOX2OT can regulate the expression of different autophagy associated factors in human cells with different mechanisms, however more remains to ...
Background:Long non-coding RNAs, as a big part of non-coding RNAs, are considered functionally more than past. These transcripts could be involved in carcinogenesis. SNHG6, as a long non-coding RNA, has been reported to be expressed more in colorectal cancer tissues than non-cancerous ones. Colorectal cancer as a malignancy needs fast prognostic and diagnostic methods for well...
Crohn disease (CD) is a type of inflammatory bowel that causes inflammation in the digestive tract. Cases CD are increasing worldwide, calling for more research to elucidate pathogenesis CD. For this purpose, usage RNA-sequencing (RNA-seq) technique increasingly appreciated, as it captures RNA expression patterns at particular time point high-throughput manner. Although many RNA-seq datasets ge...
Nucleic acids play different roles besides storing information and proteins coding. For example, single-stranded nucleic acids can fold into complicated structures with capability of molecular detection, catalyzing bioreactions and therapy. The development of RNA-based therapies has been rapidly progressed in the recent years. RNA aptamers are biomolecules with a size of 10 to 50 nm that can be...
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