introduction: burkitt lymphoma (bl) is rare, but an aggressive malignancy. central nervous system burkitt lymphoma (cnsbl) is very rare. cns burkitt’s lymphoma is treated with high-dose chemotherapy and radiation. radiotherapy in children younger than three years old may cause major cns damage. case report: a three-year-old boy presented with painful proptosis of the left eye. he underwent aden...

Introduction . The development of technologies for molecular genetic typing tumors the central nervous system (CNS) has significantly increased specificity traditional histological and immunohistochemical research methods. As a result, completely new variants have appeared, as well improved results treatment with long-term favorable prognosis. Thanks to biomarkers, among morphologically similar...

meningioma is usually a benign central nervous system (cns) tumor. metastasis is rare; however if it does occur the most metastatic sites are the liver and lungs. here, two cases of cns meningioma with metastasis to cervical lymph nodes are reported. the first case, a 48 year-old man developed cervical lymph node metastasis nine years after primary tumor diagnosis. the second case, a 23 year-ol...

primary and secondary malignant central nervous system (cns) tumors are devastating invasive tumors able to give rise to many kinds of differentiated tumor cells. glioblastoma multiform (gbm), is the most malignant brain tumor, in which its growth and persistence depend on cancer stem cells with enhanced dna damage repair program that also induces recurrence and resists current chemo- and radio...

 Primary and secondary malignant central nervous system (CNS) tumors are devastating invasive tumors able to give rise to many kinds of differentiated tumor cells. Glioblastoma multiform (GBM), is the most malignant brain tumor, in which its growth and persistence depend on cancer stem cells with enhanced DNA damage repair program that also induces recurrence and resists current chemo- and radi...

Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly aggressive, poorly differentiated embryonal tumors occurring predominantly in young children but also affecting adolescents and adults. Herein, we demonstrate that a significant proportion of institutionally diagnosed CNS-PNETs display molecular profiles indistinguishable from those of various other well-defin...

In 2021, the WHO revised its classification of central nervous system (CNS) tumors, which has resulted in changes to both diagnostic and treatment landscapes. At NCCN 2023 Annual Conference, this tumor board–style presentation featured 4 case studies demonstrate an evidence-based approach patients with various WHO-defined types diffuse glioma. The Guidelines have been updated reflect reclassifi...