Platelet-mediated clumping of Plasmodium falciparum infected erythrocytes (IEs) is a frequently observed parasite adhesion phenotype. The importance of clumping in severe malaria and the molecular mechanisms behind this phenomenon are incompletely understood. Three platelet surface molecules have previously been identified as clumping receptors: CD36, globular C1q receptor (gC1qR/HABP1/p32), an...

Encapsulated and nonencapsulated strains of Staphylococcus aureus which lack coagulase or clumping factor (bound coagulase), or both, were examined for the antigen associated with the fibrinogen-cell clumping reaction. Extracts of the cells were tested for the ability to react with fibrinogen or to inhibit fibrinogen precipitation. Antisera prepared against encapsulated (coagulase-positive, clu...

Clumping reaction, using standard suspension of Staph. aureus Newman D-2-C strain and various substrates, was quantitatively tested. It has been shown that clumping occurs in fibrin lysate containing soluble fibrin monomer complexes unclottable by thrombin. The reaction was positive with staphylococcal strains possessing clumping factor regardless of staphylocoagulase production. Clumping react...

In contrast to herbaceous canopies and forests, savannas are grassland ecosystems with sparsely distributed individual trees, so the canopy is spatially heterogeneous and open, whereas the woody cover in savannas, e.g., tree cover, adversely affects ecosystem structures and functions. Studies have shown that the dynamics of canopy structure are related to available water, climate, and human act...

Platelets may play a role in the pathogenesis of human cerebral malaria (CM), and they have been shown to induce clumping of Plasmodium falciparum-parasitized red blood cells (PRBCs) in vitro. Both thrombocytopenia and platelet-induced PRBC clumping are associated with severe malaria and, especially, with CM. In the present study, we investigated the occurrence of the clumping phenomenon in pat...

Energy efficient clumping formation of nodes in Mobile Ad-Hoc Networks (MANETs) is very important as nodes in MANETs typically activate unattended with a limited power source. Energy efficient clumping formation in MANET is one of the major issue because energy of one node in clumping may affect all other nodes and also effect on the life time of the Clumping Head.In this paper, propose a newal...

Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is an adhesive phenotype commonly found in field isolates that has previously been associated with severe malaria. Here, clumping was assessed in 131 isolates from Malian children. The clumping phenotype was seen in 6% (N = 51) of uncomplicated malaria, 24% (N = 51) of severe malaria, and 45% (N = 29) of high parasitemia ...

negative strains according to the slide clumping reaction, were the test organisms. In the clumping factor-positive series, there were 13 coagoulase-positive (including the Smith strain) and three coagulase-negative organisms. The clumping factor-negative group was composed of eight coagulase-positive and six coagulase-negative staphylococci. Of the coagulase-positive, clumping factor-negative ...

The evolution of multicellular organisms represents one of the major evolutionary transitions in the history of life. A potential advantage of forming multicellular clumps is that it provides an efficiency benefit to pre-existing cooperation, such as the production of extracellular 'public goods'. However, this is complicated by the fact that cooperation could jointly evolve with clumping, and ...