Clotrimazol é reduzido em eletrodo de mercúrio em tampão fosfato pH > 6 através de um processo reversível de um elétron. O processo eletródico apresenta forte efeito de adsorção, o qual pode ser minimizado na presença de Triton X-100. Clotrimazol pode ser determinado em níveis de 50 ng mL-1 quando pré-acumulado durante 3 min à –0,20 V. O método proposto foi aplicado para determinação do fármaco...

The platelet procoagulant response requires a sustained elevation of the intracellular Ca2+ concentration, [Ca2+]i, causing exposure of phosphatidylserine (PS) at the outer surface of the plasma membrane. An increased [Ca2+]i also activates Ca2+-dependent K+ channels. Here, we investigated the contribution of the efflux of K+ ions on the platelet procoagulant response in collagen-thrombin-activ...

The platelet procoagulant response requires a sustained elevation of the intracellular Ca2 concentration, [Ca2 ]i, causing exposure of phosphatidylserine (PS) at the outer surface of the plasma membrane. An increased [Ca2 ]i also activates Ca2 -dependent K channels. Here, we investigated the contribution of the efflux of K ions on the platelet procoagulant response in collagen-thrombin–activate...

background and aims: candida albicans is the most common cause of vulvovaginitis candidiasis that is the most common vaginitis in human. it is estimated that more than 90% of these infections are caused by candida albicans. medical treatment for these infections is carried out with chemotherapeutic drugs such as azoles. the increasing resistance of c. albicans to the azoles as well as their pro...

Two silver nanoparticles containing compounds were prepared by simple chemical reactions and characterized X-ray diffraction (XRD), infra-red spectrum (FTIR) atomic force microscope (AFM). These functionalized used to study their biological activity against four types of fungi. proved have high inhibition effect all studied Due the presence which increases nystatin clotrimazol interact with