Clostridium perfringens type A produces a variety of toxins. It has been shown that the alpha toxin (lecithinase) produced by this organism apparently plays a major role in its virulence (Evans, 1947) using the guinea pig as the test animal. If lecithinase is necesary for virulence, the organisms should be avirulent when the lecithinase is inhibited. Calcium ion is necessary for lecithinase act...

Four hundred and fifty 1-d-old male Lingnan Yellow broiler chickens were used to investigate the effects of Clostridium butyricum on growth performance, immune function, and cecal microflora. The birds were randomly assigned to 5 treatments and offered the same antibiotic-free basal diets for 42 d. The treatments were as follows: no addition (control), 1 × 10(7) cfu C. butyricum/kg of diet (CB1...

Background and Aims: Clostridium difficile is an identified cause of antibiotic-associated diarrhea, antibiotic-associated colitis, pseudomembranous colitis and nosocomial diarrhea. The objective of this survey was to determine molecular analysis of toxigenic Clostridium difficile isolates from hospital environment in Tehran tertiary medical centers. Materials and Methods: In this descriptiv...

background detection of fastidious enteropathogenic bacteria in fecal samples of patients with gastroenteritis is a challenge in clinical microbiological laboratories. objectives the aim of this study was to compare the detection limits of the pcr and culture methods for the diagnosis of campylobacter spp., yersinia spp., clostridium perfringens, and clostridium difficile in human stool samples...

Clostridium difficileisa binding warm-positive rod and anaerobic organism, which was first described in 1935 as Bacillus difficile. Epidemiology of CDI has changed considerably on 2000. Occurrence and severity of the disease  including ulcerative colitis(inflammation of the colon), colectomy(colon section) and mortality had increased. Recent studies have reported Clostridium difficile prevalenc...