introduction: phonophoresis is the use of ultrasound to enhancing cellular drug delivery through the skin. in this study the effect of clobethasole and hydrocortisone ointments phonophoresis on pain, knee osteoarthritis and some other symptoms was studied. methods: an experimental single blind randomized clinical trial (rct) was used. an available sampling technique was used for selection of pa...

Introduction: Phonophoresis is the use of ultrasound to enhancing cellular drug delivery through the skin. In this study the effect of clobethasole and hydrocortisone ointments phonophoresis on pain, knee osteoarthritis and some other symptoms was studied. Methods: An experimental single blind randomized clinical trial (RCT) was used. An available sampling technique was used for selection o...

The partition coefficients (Kps) of six anti-inflammatory steroid drugs, dexamethasone (DMS), betamethasone (BMS), triamcinolone acetonide (TCLA), fluocinolone acetonide (FCLA), betamethasone 17,21-dipropionate (BMSDP), and clobetasole propionate (CBSP), for phosphatidylcholine (PC), and PC-cholesterol small unilamellar vesicles (SUVs) were determined by a second-derivative spectrophotometric m...