normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : vitiligo is an acquired, autoimmune melanocytic disorder characterized by circumscribed depigmented macules and patches. it affects approximately 0.5-2% of the general population worldwide. many medical treatments have been attempted with partial success, but there has been no previous trial on the combination...

BACKGROUND No controlled data is available till date comparing topical tazarotene and clobetasol in Indian psoriatic patients. OBJECTIVE The aim was to compare the clinical efficacy of 12 weeks of once-daily tazarotene 0.1% cream with that of once-daily clobetasol propionate 0.05% cream in the treatment of patients with chronic plaque psoriasis. METHODS About 36 patients with bilaterally sy...

A rapid, simple to use and low-cost thin-layer chromatographic procedure in normal phase system with densitometric detection at 246 nm was carefully validated according to the International Conference on Harmonisation (ICH) guidelines for assay of clobetasol propionate in topical solution containing clobetasol propionate in quantity 0.50 mg/mL. The adopted thin-layer chromatographic (TLC)-densi...

BACKGROUND Oral lichen planus (OLP) is a chronic inflammatory disease that can be painful, especially in the atrophic and erosive forms. Several drugs have been used with varying results, but most treatments are empirical, and do not have adequate control groups or correct study designs. OBJECTIVES To compare the effectiveness of clobetasol and ciclosporin in the topical management of OLP and...

Sir, Urticarias unresponsive to antihistamines are frustrating for both physicians and patients. In severe cases, steroids or cyclosporine may be needed.[1] This retrospective observation highlights the potential of warfarin in managing chronic idiopathic urticaria (CIU). halobetasol ointment (P = 0.005), clobetasol ointment and halobetasol ointment (P = 0.015) and halobetasol cream and halobet...

Clobetasol propionate is a super-high potent class 1 topical corticosteroid available in several formulations, including a spray formulation that is approved for use up to 4 weeks in patients aged 18 years and older with moderate to severe plaque psoriasis. The efficacy and safety of clobetasol propionate spray 0.05% has been extensively evaluated in clinical trials in more than 2200 patients w...

BACKGROUND Oral lichen planus (OLP) is believed to result from an abnormal T-cell mediated immune response. The most useful agent in the treatment is corticosteroids. The present study will be aimed at evaluation of therapeutic efficiency of two corticosteroids triamcinolone acetonate (0.1%) and clobetasol propionate with tacrolimus orabase (0.03%), an immunomodulator in the management of OLP. ...

Widespread application of clobetasol propionate resulted in suppression of the hypothalamic pituitary axis in four patients. Three patients showed Cushigoid features and developed symptoms of adrenocortical insufficiency on withdrawal of clobetasol.

introduction vitiligo is an acquired pigmentary disorder of the skin and has significant harmful effects on the appearance and consequently social functions of the patients. there is no universally effective treatment for this disease, but topical steroids and levamisole have been used. this study evaluates the effects of levamisole and clobetasol with that of clobetasol in the treatment of vit...