نتایج جستجو برای: cloaca

تعداد نتایج: 499  

Journal: :Journal of pediatric urology 2007
Dagan Jenkins Maria Bitner-Glindzicz Louise Thomasson Sue Malcolm Stephanie A Warne Sally A Feather Sarah E Flanagan Sian Ellard Coralie Bingham Lane Santos Mark Henkemeyer Andrew Zinn Linda A Baker Duncan T Wilcox Adrian S Woolf

OBJECTIVES 'Persistent cloaca' is a severe malformation affecting females in which the urinary, genital and alimentary tracts share a single conduit. Previously, a Uroplakin IIIA (UPIIIA) mutation was reported in one individual with persistent cloaca, and UPIIIA, Sonic Hedgehog (SHH), Ephrin B2 (EFNB2) and Hepatocyte Nuclear Factor 1beta (HNF1beta) are expressed during the normal development of...

2015
Daisuke Matsumaru Aki Murashima Junichi Fukushima Syuhei Senda Shoko Matsushita Naomi Nakagata Masayasu Miyajima Gen Yamada

The division of the embryonic cloaca is the most essential event for the formation of digestive and urinary tracts. The defective development of the cloaca results in anorectal malformations (ARMs; 2-5 per 10,000 live births). However, the developmental and pathogenic mechanisms of ARMs are unclear. In the current study, we visualized the epithelia in the developing cloaca and nephric ducts (ND...

Journal: :Journal of the American Society of Nephrology : JASN 2018
Masato Hoshi Antoine Reginensi Matthew S Joens James A J Fitzpatrick Helen McNeill Sanjay Jain

The epithelial Wolffian duct (WD) inserts into the cloaca (primitive bladder) before metanephric kidney development, thereby establishing the initial plumbing for eventual joining of the ureters and bladder. Defects in this process cause common anomalies in the spectrum of congenital anomalies of the kidney and urinary tract (CAKUT). However, developmental, cellular, and molecular mechanisms of...

Journal: :Journal of Diagnostic Medical Sonography 2001

Journal: :Nature 1869

Journal: :Veterinary pathology 1996
C E Dean C K Cebra A A Frank

Three newborn calves were affected by caudal spinal dysgenesis or agenesis (coccygeal vertebra) and persistent cloaca. The cloacas were lined by a mixture of transitional and colonic epithelium. The vertebral column of one calf was internalized into the cloaca. The association of persistent cloaca and caudal spinal anomalies is thought to be related to cell loss in the caudal cell mass, which a...

2014
Laura A. Runck Anna Method Andrea Bischoff Marc Levitt Alberto Peña Margaret H. Collins Anita Gupta Shiva Shanmukhappa James M. Wells Géraldine Guasch

Anorectal malformations are congenital anomalies that form a spectrum of disorders, from the most benign type with excellent functional prognosis, to very complex, such as cloaca malformation in females in which the rectum, vagina and urethra fail to develop separately and instead drain via a single common channel into the perineum. The severity of this phenotype suggests that the defect occurs...

2013
Aysenur Cerrah Celayir Gökmen Kurt Ceyhan Sahin Inanç Cici

BACKGROUND Hydrometrocolpos (HMC) develops as a result of vaginal outflow obstruction and the accumulation of secretions. It might be secondary to persistent cloaca, urogenital sinus, some syndromes, presence of the vaginal septum, vaginal atresia, and imperforate hymen. Each of them has different treatment options and follow-up protocols. This study was performed to identify the etiology and t...

Journal: :Human molecular genetics 2011
Krasimir Slanchev Michael Pütz Annette Schmitt Albrecht Kramer-Zucker Gerd Walz

NPHP4 mutations cause nephronophthisis, an autosomal recessive cystic kidney disease associated with renal fibrosis and kidney failure. The NPHP4 gene product nephrocystin-4 interacts with other nephrocystins, cytoskeletal and ciliary proteins; however, the molecular and cellular functions of nephrocystin-4 have remained elusive. Here we demonstrate that nephrocystin-4 is required for normal cl...

2009
FRANCINE GRIMONT PATRICK A.D. GRIMONT

The genus Enterobacter was first proposed by Hormaeche and Edwards (1960a). However, the history of some species now placed in the genus Enterobacter can be traced, albeit with some confusion, to the end of the 19th century. “Bacillus lactis aerogenes” was isolated by Escherich (1885) from milk and renamed “Bacillus aerogenes” by Kruse (1896) and “Aerobacter aerogenes” by Beijerinck (1900). Unt...

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