conclusions imp3 immunoreactivity was associated with poor differentiation of tumor yet not associated with tumor size depth of invasion or lymph node involvement. results immunoreactivity pattern of imp3 was cytoplasmic in different clinicopathologic findings. among different clinicopathologic findings, we found a statistical relationship between tumor differentiation and imp3 (p = 0.047); so ...

a rare case of splenic harmartoma in a 31 year old female is reported. she was admitted with splenomegaly, fever and chronic history of epistaxis. routine hematological survey revealed pancytopenia and mild hypercellular marrow. abdominal sonography showed a space-occupying lesion in the spleen which was suspected as malignant tumor. splenectomy was performed and histologic findings were diagno...

We present clinicopathologic findings in a patient treated with intraarterial thrombolysis and angioplasty for vertebrobasilar thrombosis. Autopsy revealed a marked inflammatory infiltrate within the vertebral artery at the site of catheter manipulation. This finding may have important implications for the use of interventional angiography in cerebrovascular disease.

The cholesterol has been reported to be associated with cancer development. The aim of our study was to investigate the serum cholesterol level (TC) in non-small cell lung cancer (NSCLC) patients and their association with clinicopathologic parameters and the prognosis. The serum cholesterol levels were evaluated in 259 resected NSCLC patients and were correlated with clinicopathologic variable...

The concept of clinicopathologic dissociation is a neglected one in medicine. It refers to the unexpected, complete absence concordance between clinical picture and underlying histopathologic finding. recognition such phenomenon generally implies radically different treatment follow-up choices. A rare phenomenon, it can however be encountered, especially field dermatoncology dermatology at larg...

primary adrenal lymphoma is extremely rare. we report a case with primary bilateral adrenal lym-phoma in a young male patient. he presented with abdominal pain and weight loss. pathologic study revealed malignant lymphoma, diffuse large cell type (t- cell origin). patient recieved combination chemotherapy and radiation therapy but 22 months after diagnosis died because of progression of dis ease

Objectives: To investigate clinicopathologic findings and gallbladder (GB) function in patients with endoscopic bile reflux at outpatients clinic. Methods: We classified endoscopic bile reflux into two groups by bile reflux index (BRI). Those who scored above 14 were the BRI (+) group, and those below 14 were the BRI (-) group. We analyzed clinical characteristics, endoscopic findings including...

PURPOSE Cancer stroma plays an important role in the progression of cancer. Although alterations in miRNA expression have been explored in various kinds of cancers, the expression of miRNAs in cancer stroma has not been explored in detail. EXPERIMENTAL DESIGN Using a laser microdissection technique, we collected RNA samples specific for epithelium or stroma from 13 colorectal cancer tissues a...

background: microsatellite instability (msi) is a mutational signature that is the hallmark of lynch syndrome, and msi testing is a cost-effective method to screen the disease. since there is no enough data about msi status and associated clinicopathologic features of hereditary nonpolyposis colorectal cancer (hnpcc) in iran, our study is a new trial to describe them in center of iran (isfahan)...

BACKGROUND This study was performed to evaluate the pattern of lymphatic metastases found by combined thoracoscopic (TS) and laparoscopic (LS) lymph node staging in esophageal cancer, and ascertain whether clinicopathologic factors may be used to guide the clinical practice of combined TS and LS staging. METHODS A retrospective study was performed in a series of 76 esophageal cancer patients ...