many studies with different results have been conducted regarding varicocelectomy in patients with subclinical varicocele and its effect on semen parameters. this clinical trial was aimed at assessing the effect of varicocelectomy on the spermiogram of patients with subclinical varicocele. a total of 142 patients with varicocele (79 clinical and 63 subclinical) took part in the study. two sperm...

Varicocele is one of the most common causes of low semen quality, which is reflected in high percentages of sperm cells with fragmented DNA. While varicocelectomy is usually performed to ameliorate a patient's fertility, its impact on sperm DNA integrity in the case of subclinical varicocele is poorly documented. In this study, multiple DNA fragmentation analyses (TUNEL, SCD, and SCSA) were per...

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. We read with interest the commentary by Drs. Basar and Kahraman (1). The authors provide a comprehensive review of sperm DNA fragmentation (SDF) from etiologies and assisted reproduction outcomes to treatment strategies. We wish to further elaborate the discussion on the use of SDF testing in managing varicocele. Vari...

PURPOSE To elucidate the impact of surgical varicocele repair on the pregnancy rate through new meta-analyses of randomized clinical trials that compared surgical varicocele repair and observation. MATERIALS AND METHODS The PubMed and Embase online databases were searched for studies released before December 2012. References were manually reviewed, and two researchers independently extracted ...

OBJECTIVE To investigate: 1) the impact of clinical varicocele on reactive oxygen species (ROS) levels in neat and washed semen in a proven fertile population; and 2) the correlation between ROS levels, testicular volume, and varicocele grade in the same population of fertile men. DESIGN Prospective controlled clinical study. SETTING Andrology laboratory at tertiary-care hospital. PATIENT...

INTRODUCTION Although the pathophysiology of the testicular damage associated with varicocele remains unclear, sperm DNA damage has been identified as a potential explanation for this cause of male infertility. The current study was designed to determine the extent of sperm nuclear DNA damage in patients with varicocele, and to examine its relationship with parameters of seminal motility. MAT...

conclusions the results showed that clinical and ultrasonographic grading to diagnose varicoceles is directly consistent together and it is possible to make them equivalent together. in addition, the age factor has not a significant impact on disease grading. methods in this cross-sectional study, 66 patients suspected of varicocele referred to urology clinic of shahid faghihi hospital in shira...

PURPOSE The aim of this study was to evaluate the relationship between the levels of reactive oxygen species (ROS) and the clinical characteristics of varicoceles among patients with varicocele-induced infertility. MATERIALS AND METHODS Ninety-eight patients with infertile varicocele and 22 control subjects without varicocele were enrolled. Blood samples were drawn from the brachial vein (BV)...

The objective of this review was to summarize the evidence concerning the benefit of varicocele treatment to improve natural fertility in subfertile males. We also analyzed the effect of varicocele treatment on conventional semen parameters and sperm functional tests. An electronic search to collect the data was performed using the PubMed/MEDLINE databases until July 2015. Data pooled from a va...

Varicocele is the most common cause of male infertility and is generally correctable or at least improvable by various surgical and radiologic techniques. Therefore, it seems simple and reasonable that varicocele should be treated in infertile men with varicocele. However, the role of varicocele repair for the treatment of subfertile men has been questioned during the past decades. Although var...