Both study designs were randomized, double-blind, placebo-controlled trials qualifying as a level of evidence Ia. In the study by Martinez, Franceschini, Patta, Quintana, Gomes, et al. (2009), half of the women received a single dose of tinidazole (2g) in addition to 2 placebo capsules while half received tinidazole (2g) supplemented with 2 capsules containing L. rhamnosus GR-1 and L. reuteri R...