BACKGROUND Candida species (sp) is implicated in causing opportunistic disseminated mycotic complications in stage II HIV patients. Cleistopholis patens is a West African medicinal tree reported to have significant antifungal activity against C. albicans. OBJECTIVES This study aimed to determine the anti-candidal activity of methanolic leaf extract of Cleistopholis patens against Candida spec...

A novel monoterpene derivative (1) and four known partially and total acetylated triand tetrarhamonoside dodecanyl ether derivatives: cleistrioside-2 (2) and cleistrioside-3 (3), cleistetroside-6 (4) and cleistetroside peracetate (5) have been isolated from the fruits of Cleistopholis patens.

new sources of botanical pesticides in the management of sitotroga cerealella (olivier) infesting rice grains are indispensable in farmers’ quest towards achieving maximum protection of their rice produce. in this study, the efficacy of root and stem bark of cleistopholis patens as an insecticidal agent against s. cerealella was investigated at 28 ± 2 ºc and 75 ± 6% relative humidity. moths wer...

BACKGROUND Cleistopholis patens (Cp) (Annonacae) is a popular medicinal herb used in the the treatment of cardiovascular disorders in Nigerian ethnomedicine. OBJECTIVES The present study investigated the effects of the aqueous leaf extract of Cp on lipid and haematological profile of hypercholesterolemic Albino rats. METHODS The animals were divided into 5 groups (A - E) of 5 animals per gr...

Aim: The methanol extract and partitioned fractions of Cleistopholis patens leaf were evaluated for antiplasmodial activities with a view to establishing its antimalarial potential identifying the most active fraction.
 Methods: was collected, authenticated, air-dried powdered. extract, prepared by maceration in tested (0-800 mg/kg) against P. berghei mice using Peter’s four-day test. Norm...